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Benchmarking a universal smoking machine adaptor for tobacco product testing.
El-Hellani, Ahmad; Watson, Clifford H; Huang, Michelle; Wilson, Clark W; Fleshman, Clint C; Tran, Hang; Chafin, Dana; McGuigan, Megan; Bravo Cardenas, Roberto; Petitti, Ryan; Pancake, Mary; Bennett, Chad; Mays, Darren; Keller-Hamilton, Brittney L; Jones, Jeremy; Ye, Wei; Schaff, Jason; Borthwick, Robert P; Williamson, Raymond L; Wagener, Theodore L; Brinkman, Marielle C.
Afiliación
  • El-Hellani A; Division of Environmental Health Sciences, The Ohio State University College of Public Health, Columbus, Ohio, USA.
  • Watson CH; Center for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
  • Huang M; Tobacco Products Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Wilson CW; Tobacco Products Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Fleshman CC; Center for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
  • Tran H; Division of Epidemeology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
  • Chafin D; Center for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
  • McGuigan M; Division of Epidemeology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
  • Bravo Cardenas R; Tobacco Products Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Petitti R; Tobacco Products Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Pancake M; Tobacco Products Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Bennett C; Tobacco Products Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Mays D; Center for Design and Manufacturing Excellence, The Ohio State University, Columbus, Ohio, USA.
  • Keller-Hamilton BL; Center for Design and Manufacturing Excellence, The Ohio State University, Columbus, Ohio, USA.
  • Jones J; Medicinal Chemistry Shared Resource, Drug Development Institute, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
  • Ye W; Center for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
  • Schaff J; Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Borthwick RP; Center for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
  • Williamson RL; Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Wagener TL; Produced Better, Columbus, Ohio, USA.
  • Brinkman MC; Center for Tobacco Products, US Food and Drug Administration, Silver Spring, Maryland, USA.
Tob Control ; 2024 Jul 15.
Article en En | MEDLINE | ID: mdl-39009449
ABSTRACT

SIGNIFICANCE:

Characterisation of tobacco product emissions is an important step in assessing their impact on public health. Accurate and repeatable emissions data require that a leak-tight seal be made between the smoking or vaping machine and the mouth-end of the tobacco product being tested. This requirement is challenging because of the variety of tobacco product mouth-end geometries being puffed on by consumers today. We developed and tested a prototype universal smoking machine adaptor (USMA) that interfaces with existing machines and reliably seals with a variety of tobacco product masses and geometries.

METHODS:

Emissions were machine-generated using the USMA and other available adaptors for a variety of electronic cigarettes (n=7 brands), cigars (n=4), cigarillos (n=2), a heated tobacco product, and a reference cigarette (1R6F), and mainstream total particulate matter (TPM) and nicotine were quantified. Data variability (precision, n≥10 replicates/brand) for all products and error (accuracy) from certified values (1R6F) were compared across adaptors.

RESULTS:

TPM and nicotine emissions generated using the USMA were accurate, precise and agreed with certified values for the 1R6F reference cigarette. Replicate data indicate that USMA repeatability across all tobacco products tested generally meets or exceeds that from the comparison adaptors and extant data.

CONCLUSION:

The USMA seals well with a variety of combustible tobacco products, e-cigarettes with differing geometries and plastic-tipped cigarillos. Variability for all measures was similar or smaller for the USMA compared with other adaptors.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Tob Control Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Tob Control Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos