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Creation of a predictive calculator to determine adequacy of occlusion of the woven endobridge (WEB) device in intracranial aneurysms-A retrospective analysis of the WorldWide WEB Consortium database.
Musmar, Basel; Adeeb, Nimer; Gendreau, Julian; Horowitz, Melanie Alfonzo; Salim, Hamza Adel; Sanmugananthan, Praveen; Aslan, Assala; Brown, Nolan J; Cancelliere, Nicole M; McLellan, Rachel M; Algin, Oktay; Ghozy, Sherief; Dibas, Mahmoud; Orscelik, Atakan; Senol, Yigit Can; Lay, Sovann V; Guenego, Adrien; Renieri, Leonardo; Carnevale, Joseph; Saliou, Guillaume; Mastorakos, Panagiotis; El Naamani, Kareem; Shotar, Eimad; Premat, Kevin; Möhlenbruch, Markus; Kral, Michael; Doron, Omer; Chung, Charlotte; Salem, Mohamed M; Lylyk, Ivan; Foreman, Paul M; Vachhani, Jay A; Shaikh, Hamza; Zupancic, Vedran; Hafeez, Muhammad U; Catapano, Joshua; Waqas, Muhammad; Tutino, Vincent M; Gokhan, Yuce; Imamoglu, Cetin; Bayrak, Ahmet; Rabinov, James D; Ren, Yifan; Schirmer, Clemens M; Piano, Mariangela; Kühn, Anna L; Michelozzi, Caterina; Elens, Stéphanie; Starke, Robert M; Hassan, Ameer E.
Afiliación
  • Musmar B; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Adeeb N; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Gendreau J; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Horowitz MA; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Salim HA; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Sanmugananthan P; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Aslan A; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Brown NJ; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Cancelliere NM; Division of Diagnostic and Therapeutic Neuroradiology, Department of Radiology, St Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • McLellan RM; Neuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
  • Algin O; Department of Radiology, Medical Faculty of Ankara University, Ankara, Turkey.
  • Ghozy S; Departments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
  • Dibas M; Departement of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
  • Orscelik A; Departments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
  • Senol YC; Departments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
  • Lay SV; Service de Neuroradiologie Diagnostique et Thérapeutique, Centre Hospitalier de Toulouse, Hôpital Purpan, Toulouse, France.
  • Guenego A; Service de Neuroradiologie Interventionnelle, Hôpital Universitaire Erasme, Bruxelles Belgique, Belgium.
  • Renieri L; Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy.
  • Carnevale J; Neurosurgery & Interventional Neuroradiology, New York Presbyterian Hospital, Weill Cornell School of Medicine, New York, NY, USA.
  • Saliou G; Service de radiodiagnostic et radiologie interventionnelle, Centre Hospitalier Vaudois de Lausanne, Lausanne, Switzerland.
  • Mastorakos P; Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • El Naamani K; Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • Shotar E; Department de Neuroradiologie, Hôpital Pitié-Salpêtrière. Université Sorbonne, Paris, France.
  • Premat K; Department de Neuroradiologie, Hôpital Pitié-Salpêtrière. Université Sorbonne, Paris, France.
  • Möhlenbruch M; Sektion Vaskuläre und Interventionelle Neuroradiologie, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Kral M; Department of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria.
  • Doron O; Neuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
  • Chung C; Departments of Radiology & Neurosurgery, NYU Langone Health Center, New York, NY, USA.
  • Salem MM; Department of Neurosurgery, University of Pennsylvania Medical Center, Pennsylvania, PA, USA.
  • Lylyk I; Equipo de Neurocirugía Endovascular y Radiología Intervencionista, Clínica La Sagrada Familia, Buenos Aires, Argentina.
  • Foreman PM; Neurosurgery Department, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
  • Vachhani JA; Neurosurgery Department, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
  • Shaikh H; Departments of Radiology & Neurosurgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ, USA.
  • Zupancic V; Subdivision of Interventional Neuroradiology, Department of Radiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
  • Hafeez MU; Department of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
  • Catapano J; Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ, USA.
  • Waqas M; Department of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
  • Tutino VM; Department of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
  • Gokhan Y; Department of Radiology, Medical Faculty of Ankara University, Ankara, Turkey.
  • Imamoglu C; Department of Radiology, Medical Faculty of Ankara University, Ankara, Turkey.
  • Bayrak A; Department of Radiology, Medical Faculty of Ankara University, Ankara, Turkey.
  • Rabinov JD; Neuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
  • Ren Y; Interventional Radiology and Neurointerventional Services, Department of Radiology, Austin Health, Melbourne, Victoria, Australia.
  • Schirmer CM; Department of Neurosurgery and Radiology, Geisinger Hospital, Danville, PA, USA.
  • Piano M; Interventistica Neurovascolare, Ospedale Niguarda Cà Granda, Milano, Italy.
  • Kühn AL; Department of Neurointerventional Radiology, UMass Memorial Hospital, Worcester, MA, USA.
  • Michelozzi C; Interventistica Neurovascolare, Ospedale San Raffaele, Milano, Italy.
  • Elens S; Interventistica Neurovascolare, Ospedale Careggi di Firenze, Florence, Italy.
  • Starke RM; Deparment of Neurosurgery, University of Miami, Miami, FL, USA.
  • Hassan AE; Deparment of Neuroscience, Valley Baptist Neuroscience Institute, Harlingen, TX, USA.
Interv Neuroradiol ; : 15910199241267320, 2024 Aug 10.
Article en En | MEDLINE | ID: mdl-39127463
ABSTRACT

BACKGROUND:

Endovascular treatment with the woven endobridge (WEB) device has been widely utilized for managing intracranial aneurysms. However, predicting the probability of achieving adequate occlusion (Raymond-Roy classification 1 or 2) remains challenging.

OBJECTIVE:

Our study sought to develop and validate a predictive calculator for adequate occlusion using the WEB device via data from a large multi-institutional retrospective cohort.

METHODS:

We used data from the WorldWide WEB Consortium, encompassing 356 patients from 30 centers across North America, South America, and Europe. Bivariate and multivariate regression analyses were performed on a variety of demographic and clinical factors, from which predictive factors were selected. Calibration and validation were conducted, with variance inflation factor (VIF) parameters checked for collinearity.

RESULTS:

A total of 356 patients were included 124 (34.8%) were male, 108 (30.3%) were elderly (≥65 years), and 118 (33.1%) were current smokers. Mean maximum aneurysm diameter was 7.09 mm (SD 2.71), with 112 (31.5%) having a daughter sac. In the multivariate regression, increasing aneurysm neck size (OR 0.706 [95% CI 0.535-0.929], p = 0.13) and partial aneurysm thrombosis (OR 0.135 [95% CI 0.024-0.681], p = 0.016) were found to be the only statistically significant variables associated with poorer likelihood of achieving occlusion. The predictive calculator shows a c-statistic of 0.744. Hosmer-Lemeshow goodness-of-fit test indicated a satisfactory model fit with a p-value of 0.431. The calculator is available at https//neurodx.shinyapps.io/WEBDEVICE/.

CONCLUSION:

The predictive calculator offers a substantial contribution to the clinical toolkit for estimating the likelihood of adequate intracranial aneurysm occlusion by WEB device embolization.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Interv Neuroradiol Asunto de la revista: NEUROLOGIA / RADIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Interv Neuroradiol Asunto de la revista: NEUROLOGIA / RADIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos