Effect of volume of water taken with diazepam tablets on absorption.
Br J Anaesth
; 58(1): 41-4, 1986 Jan.
Article
en En
| MEDLINE
| ID: mdl-3942669
ABSTRACT
Thirty-three patients received either 10 ml (group A) or 50 ml (group B) of water with diazepam tablets as premedication while in the supine position. Plasma diazepam concentrations were measured, a delay in the attainment of the peak plasma concentration being taken as an indication of delayed absorption and oesophageal hold-up. There was no difference between the two groups, although in an important minority (16.7% (group A) and 20% (group B], absorption was delayed to beyond 60 min. There was a wide scatter of plasma diazepam concentrations in both groups. Dysphagia during swallowing did not appear to delay absorption.
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Bases de datos:
MEDLINE
Asunto principal:
Medicación Preanestésica
/
Diazepam
/
Ingestión de Líquidos
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Br J Anaesth
Año:
1986
Tipo del documento:
Article