Malnutrition and humoral immunity: short-term acute nutritional deprivation.
Surgery
; 98(4): 769-76, 1985 Oct.
Article
en En
| MEDLINE
| ID: mdl-4049248
ABSTRACT
The effects of short-term acute nutritional deprivation and refeeding on immune function was investigated in rats. Animals previously sensitized to keyhole-limpet hemocyanin were starved for 72 hours and refed for 7 days. Recall skin testing with keyhole-limpet hemocyanin and immunization with tetanus toxoid (TT) were used to assess delayed-type hypersensitivity (DTH) and humoral immune responses. DTH was maximally depressed late, after refeeding had begun. Anti-TT responses were depressed early during starvation. Neither DTH nor anti-TT responses had returned to normal after a period of refeeding sufficient to restore weight. The data indicate that short-term acute nutritional deprivation may contribute to acquired immunodeficiency in patients undergoing surgery.
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Bases de datos:
MEDLINE
Asunto principal:
Inanición
/
Alimentos
/
Hipersensibilidad Tardía
/
Trastornos Nutricionales
Límite:
Animals
Idioma:
En
Revista:
Surgery
Año:
1985
Tipo del documento:
Article