Taxonomic distribution of the antigen eliciting bactericidal antibody for Bordetella pertussis.
J Gen Microbiol
; 87(2): 239-44, 1975 Apr.
Article
en En
| MEDLINE
| ID: mdl-49392
ABSTRACT
Strains of Bordetella pertussis varied in their ability to elicit (in mice) an antibody bactericidal for an antiserum-sensitive strain of B. pertussis, although antibody was usually detectable after only one injection. High titres were produced by a course of seven injections with all strains of B. pertussis tested (six of phase I and three of phase IV) but not with three strains of other Bordetella species nor with two unrelated organisms, a finding of possible taxonomic value. Preliminary investigations have not revealed whether strain vaiations are due to quantitative or qualitative differences in either the bacterial lipopolysaccharide or the carrier protein necessary for antibody production, or whether they may be due to differences in heat lability of 'bactericidal antigen'.
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Bases de datos:
MEDLINE
Asunto principal:
Bordetella pertussis
/
Vacuna contra la Tos Ferina
/
Formación de Anticuerpos
/
Antígenos Bacterianos
Tipo de estudio:
Qualitative_research
Límite:
Animals
Idioma:
En
Revista:
J Gen Microbiol
Año:
1975
Tipo del documento:
Article