Expression of Tac antigen on activated normal human B cells.
J Exp Med
; 160(2): 612-7, 1984 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-6088664
ABSTRACT
Two-color fluorescence analysis revealed that Tac antigen, which was previously reported to be restricted to T cells, was expressed on a proportion of normal B cells activated by Staphylococcus aureus Cowan I (SAC). Immunoaffinity-purified interleukin 2 (IL-2) induced the proliferation of SAC-activated B cells, and the proliferation was completely inhibited by anti-Tac antibody, which blocked the membrane binding and action of IL-2. These results suggest that an IL-2 receptor system is directly involved in the B cell immune response.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Linfocitos B
/
Activación de Linfocitos
/
Antígenos de Superficie
Límite:
Humans
Idioma:
En
Revista:
J Exp Med
Año:
1984
Tipo del documento:
Article