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Specific antigen in serum of patients with colon carcinoma.
Science ; 212(4490): 53-5, 1981 Apr 03.
Article en En | MEDLINE | ID: mdl-6163212
The binding of monoclonal antibody specific for colon carcinoma was inhibited by serum from patients with adenocarcinoma of the colon but not by serum from patients with other bowel diseases or from healthy volunteers. Of other malignancies studied, serum from two patients with gastric carcinoma and two patients with pancreatic carcinoma also inhibited the specific binding of monoclonal antibody. The levels of carcinoembryonic antigen in these serum samples were not correlated with their levels of binding inhibition. Such monoclonal antibodies may prove useful for the detection of colorectal carcinoma.
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Bases de datos: MEDLINE Asunto principal: Adenocarcinoma / Neoplasias del Colon / Antígenos de Neoplasias Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Science Año: 1981 Tipo del documento: Article
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Bases de datos: MEDLINE Asunto principal: Adenocarcinoma / Neoplasias del Colon / Antígenos de Neoplasias Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Science Año: 1981 Tipo del documento: Article