Total body irradiation in chronic myeloid leukemia.
Int J Radiat Oncol Biol Phys
; 9(4): 497-500, 1983 Apr.
Article
en En
| MEDLINE
| ID: mdl-6343310
ABSTRACT
Total body irradiation (TBI), given as 10 rad daily for five days a week for a total dose of 150 rad has been used in an attempt to control the chronic phase of chronic myeloid leukemia (CML). Thirteen patients with CML received fractionated TBI leading to rapid and good control of WBC count without any adverse reaction. The chronic phase of CML could also be controlled with TBI, even in three patients who were resistant to busulfan. Following TBI, WBC count remained under control for a period of 32 weeks as compared to 40 weeks following busulfan alone. Repeat TBI was also well tolerated with good response. It appears that TBI is an effective and safe therapy for controlling the chronic phase of CML.
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Bases de datos:
MEDLINE
Asunto principal:
Leucemia Mieloide
Límite:
Adolescent
/
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Int J Radiat Oncol Biol Phys
Año:
1983
Tipo del documento:
Article