Ester of 6-cis-dialkylamino-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-5-trans-ol with hypotensive and other activities.
Farmaco Sci
; 36(3): 225-36, 1981 Mar.
Article
en En
| MEDLINE
| ID: mdl-7227506
ABSTRACT
Three series of esters of 6-cis-dialkylamino-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-5-trans-ol (dialkylamino = pyrrolidino, piperidino, morpholino) are described. A number of these compounds showed strong hypotensive activity in rats, as well as infiltration anesthesia and antiarrhythmic activity in mice. The lowering effects on heart rate in rats are also described.
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Bases de datos:
MEDLINE
Asunto principal:
Compuestos Bicíclicos con Puentes
/
Hidrocarburos Aromáticos con Puentes
/
Antihipertensivos
Límite:
Animals
Idioma:
En
Revista:
Farmaco Sci
Año:
1981
Tipo del documento:
Article