Deficit of T-cell recovery after allogeneic bone marrow transplantation in chronic myeloid leukemia patients.
Anticancer Res
; 15(4): 1553-60, 1995.
Article
en En
| MEDLINE
| ID: mdl-7654044
ABSTRACT
The immunological reconstitution that follows bone marrow transplantation (BMT) was studied in 40 leukaemia patients 19 with chronic myeloid leukaemia (CML), 12 with acute myeloid leukaemia (AML) and the remaining 9 with acute lymphoblastic leukaemia (ALL). The recovery of the CML group was slower than that of the ALL and AML groups. This difference was produced by the T cell compartment, as NK cell activity and B cell numbers did not differ significantly. Factors such as conditioning treatment and graft versus host disease (GVHD) prophylaxis were analysed. Our experience suggests that all leukaemia patients should not be considered as one group when analysing their immunological reconstitution, as factors related to the original disease may affect their outcome.
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Bases de datos:
MEDLINE
Asunto principal:
Linfocitos T
/
Leucemia Mielógena Crónica BCR-ABL Positiva
/
Trasplante de Médula Ósea
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Anticancer Res
Año:
1995
Tipo del documento:
Article
País de afiliación:
Brasil