Beta-globin gene cluster haplotypes of Amerindian populations from the Brazilian Amazon region.
Hum Hered
; 44(3): 142-9, 1994.
Article
en En
| MEDLINE
| ID: mdl-8039797
ABSTRACT
We have determined the beta-globin cluster haplotypes for 80 Indians from four Brazilian Amazon tribes Kayapó, Wayampí, Wayana-Apalaí, and Arára. The results are analyzed together with 20 Yanomámi previously studied. From 2 to 4 different haplotypes were identified for each tribe, and 7 of the possible 32 haplotypes were found in a sample of 172 chromosomes for which the beta haplotypes were directly determined or derived from family studies. The haplotype distribution does not differ significantly among the five populations. The two most common haplotypes in all tribes were haplotypes 2 and 6, with average frequencies of 0.843 and 0.122, respectively. The genetic affinities between Brazilian Indians and other human populations were evaluated by estimates of genetic distance based on haplotype data. The lowest values were observed in relation to Asians, especially Chinese, Polynesians, and Micronesians.
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Bases de datos:
MEDLINE
Asunto principal:
Haplotipos
/
Globinas
/
Indígenas Sudamericanos
/
Familia de Multigenes
Límite:
Humans
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Hum Hered
Año:
1994
Tipo del documento:
Article
País de afiliación:
Brasil