The determination of liposome captured volume.
Chem Phys Lipids
; 64(1-3): 197-217, 1993 Sep.
Article
en En
| MEDLINE
| ID: mdl-8242834
ABSTRACT
Manipulating the process by which lipids assemble to form bilayer membranes has produced a myriad of protocol-dependent liposome types. For each of these systems the arrangement of bilayers is characteristic and can be described by parameters such as aqueous entrapment per mole lipid or captured volume, vesicle size distribution, the average number of lamellae per vesicle and shape. For specific applications as model systems or drug delivery systems specific characteristics are desired. Consequently over the years many techniques have evolved to better quantitate these parameters. Here we focus on and detail several methods to quantitate liposome captured volume. We also briefly describe the available methods to measure the other aforementioned physical properties and discuss their interdependency with captured volume.
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Bases de datos:
MEDLINE
Asunto principal:
Fosfatidilcolinas
/
Membrana Dobles de Lípidos
/
Liposomas
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Chem Phys Lipids
Año:
1993
Tipo del documento:
Article