Functional brain imaging at 1.5 T using conventional gradient echo MR imaging techniques.
Magn Reson Imaging
; 11(4): 451-9, 1993.
Article
en En
| MEDLINE
| ID: mdl-8316058
ABSTRACT
There is considerable interest in the use of MR imaging to study brain function. Recently, it has been demonstrated that small changes in signal intensity occur in the visual cortex in T2*-weighted imaging in response to appropriate visual stimuli. Similar responses to activation have also been recorded in motor cortex as well as frontal lobes. To date most of these studies have been carried out at very high field strength or they have used echo planar imaging. We report our preliminary results showing that the effects of activation of visual and motor areas of the brains of normal volunteers can be recorded using conventional MR imaging methods on a standard 1.5 T clinical scanner. Using gradient-echo imaging sequences, we have been able to map activated visual and motor cortex with high spatial resolution in multiple planes, and are using this technique to examine the relationship between physiological response and stimulus parameters. Signal changes of the order of 2-12% in images with TE = 45 msec, TR = 120 msec, and alpha = 40 degrees, permit excellent depiction of the regions affected.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Corteza Visual
/
Encéfalo
/
Imagen por Resonancia Magnética
/
Corteza Motora
Límite:
Humans
Idioma:
En
Revista:
Magn Reson Imaging
Año:
1993
Tipo del documento:
Article