Quinazolinone derivatives: synthesis and binding evaluation on cholecystokinin receptors.
Farmaco
; 51(5): 333-9, 1996 May.
Article
en En
| MEDLINE
| ID: mdl-8767843
ABSTRACT
A series of 2-methyl-3-amino-4(H)-quinazolinone and of 2-phenyl-3-amino-4(H)-quinazolinone derivatives were synthesized and examined for their CCK receptor affinities. These compounds displayed micromolar affinities for CCK-B rather than CCK-A receptor and the obtained results confirm that the 4(3H)-quinazolinone nucleous represent a useful template for the development of selective CCK-B receptor ligands.
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Bases de datos:
MEDLINE
Asunto principal:
Quinazolinas
/
Receptores de Colecistoquinina
Límite:
Animals
Idioma:
En
Revista:
Farmaco
Asunto de la revista:
FARMACOLOGIA
/
QUIMICA
Año:
1996
Tipo del documento:
Article
País de afiliación:
Italia