New structures of allosteric proteins revealing remarkable conformational changes.
Curr Opin Struct Biol
; 6(6): 824-9, 1996 Dec.
Article
en En
| MEDLINE
| ID: mdl-8994883
ABSTRACT
New three-dimensional structures of allosteric proteins reveal they have a flexible architecture that is instrumental to the regulation of protein function. Highlights are the structures of GroEL, pyruvate kinase, D-3-phosphoglycerate dehydrogenase and the acetylcholine receptor. Furthermore, significant progress in understanding the nature of the intermediates involved in an allosteric reaction has been achieved through recent spectroscopic and crystallographic studies on haemoglobin.
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Bases de datos:
MEDLINE
Asunto principal:
Proteínas
Idioma:
En
Revista:
Curr Opin Struct Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
1996
Tipo del documento:
Article
País de afiliación:
Italia