[Cardiac myxoma. Anatomo-clinical and immunohistochemical study of 13 cases]. / Mixomas cardíacos. Estudio anatomoclínico e inmunohistoquímico de 13 casos.
Rev Esp Cardiol
; 49(10): 741-6, 1996 Oct.
Article
en Es
| MEDLINE
| ID: mdl-9036476
ABSTRACT
INTRODUCTION:
Cardiac myxomas are the most frequent benign heart tumors, and have an uncertain histogenesis. An endothelial, subendocardial and an undifferentiated mesenchymal cell origin with vasoformative characteristics has been suggested. The aim of this study was to make a review the cardiac myxomas at our institution paying special attention to its histogenesis. MATERIAL ANDMETHODS:
We reviewed the clinico-pathological features of the 13 cardiac myxomas studied at our hospital, and we stained them with immunohistochemical stains.RESULTS:
The average age on presentation was 62.8 years. 12 cases were left atrial, one of them with cerebral metastasis. The average size was 6.3 cm. Microscopically all of them were composed of a myxoid-matrix with spindled cells and small neoformed vessels. The tumors were completely positive for Vimentin and randomly positive with Actin and VIII-RA. CAM 5.2 was strictly negative.CONCLUSION:
These results show that these kinds of tumors are neoplasms arising from mesenchymal pluripotential cells which are capable of many types of differentiation (endothelium, etc).
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Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Cardíacas
/
Mixoma
Tipo de estudio:
Observational_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Rev Esp Cardiol
Año:
1996
Tipo del documento:
Article