Noise stress does not modulate effects of smoking/nicotine on beta-endorphin, cortisol, ACTH, glucose, and mood.
Psychopharmacology (Berl)
; 130(3): 197-202, 1997 Apr.
Article
en En
| MEDLINE
| ID: mdl-9151352
ABSTRACT
Noise-dependent effects of smoking multiple cigarettes on subjective state and blood concentrations of ACTH, beta-endorphin, cortisol, and glucose were assessed in a repeated measures design where noise level (high versus minimal) was crossed with nicotine dose (quasi-ad lib own brand versus 1.0 mg FTC nicotine machine-delivered dose versus 0.05 mg FTC nicotine machine-delivered dose). Cortisol and ACTH were increased by nicotine, but not by noise and there was no noise by dose interaction. In contrast, nicotine did not increase beta-endorphin in either noise condition and there was no dose by noise interaction for beta-endorphin. However, noise was associated with a modest increase in beta-endorphin. The effects of nicotine on blood glucose varied as a function of the number of cigarettes smoked. However, the effects of nicotine on glucose, hormones, and subjective state did not vary as a function of noise stress.
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Bases de datos:
MEDLINE
Asunto principal:
Glucemia
/
Hidrocortisona
/
Betaendorfina
/
Fumar
/
Hormona Adrenocorticotrópica
/
Afecto
/
Nicotina
/
Ruido
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Psychopharmacology (Berl)
Año:
1997
Tipo del documento:
Article
País de afiliación:
Estados Unidos