Variability analysis of HIV-1 gp120 V3 region: I. Point estimators for the amino acid distribution characteristics.
J Biomol Struct Dyn
; 15(2): 217-29, 1997 Oct.
Article
en En
| MEDLINE
| ID: mdl-9399150
ABSTRACT
Enumerating procedure for symbol sequences is proposed. Relationship between Hamming distance for symbol sequences and Euclidean distance for corresponding enumerations is established, and more universal Hamming-transformed Euclidean measure is constructed. A distribution function of amino acid substitutions and some of its point estimators (consensus, subconsensus, sample mean, sample central moments and asymmetry coefficient) are introduced. Hamming-transformed Euclidean measures between consensus, subconsensus and sample means for ten HIV-1 taxons of gp120 V3 regions are calculated. It is demonstrated that these taxons have a complicated pattern which is significant for their classification.
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Bases de datos:
MEDLINE
Asunto principal:
Fragmentos de Péptidos
/
Variación Genética
/
Proteína gp120 de Envoltorio del VIH
/
VIH-1
Idioma:
En
Revista:
J Biomol Struct Dyn
Año:
1997
Tipo del documento:
Article
País de afiliación:
Rusia