Detalhe da pesquisa
1.
Design, synthesis, molecular modelling and biological evaluation of novel 6-amino-5-cyano-2-thiopyrimidine derivatives as potent anticancer agents against leukemia and apoptotic inducers.
J Enzyme Inhib Med Chem
; 39(1): 2304625, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348824
2.
Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells.
J Enzyme Inhib Med Chem
; 38(1): 405-422, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458403
3.
Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents.
J Enzyme Inhib Med Chem
; 37(1): 1821-1837, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35762086
4.
Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition.
J Enzyme Inhib Med Chem
; 36(1): 977-986, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33957835
5.
Synthesis of Novel 2-Thiouracil-5-Sulfonamide Derivatives as Potent Inducers of Cell Cycle Arrest and CDK2A Inhibition Supported by Molecular Docking.
Int J Mol Sci
; 22(21)2021 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769385
6.
Novel antiviral compounds against gastroenteric viral infections.
Arch Pharm (Weinheim)
; 348(3): 194-205, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25704120
7.
Pyrrolopyrazoles: Synthesis, Evaluation and Pharmacological Screening as Antidepressant Agents.
Med Chem
; 15(8): 911-922, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30406741
8.
Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles.
Anticancer Agents Med Chem
; 17(7): 1014-1025, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28042776
9.
Synthesis and kinetic testing of new inhibitors for a metallo-ß-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa.
Eur J Med Chem
; 46(12): 6075-82, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22051063