Detalhe da pesquisa
1.
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.
Cell
; 184(15): 4032-4047.e31, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34171309
2.
SnapShot: Splicing Alterations in Cancer.
Cell
; 180(1): 208-208.e1, 2020 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31951519
3.
NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia.
Nat Immunol
; 23(10): 1424-1432, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36138187
4.
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Cell
; 170(6): 1079-1095.e20, 2017 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28823558
5.
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies.
Mol Cell
; 84(10): 1886-1903.e10, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38688280
6.
RBM33: A new regulator of N-6-methyladenosine (m6A) methylation.
Mol Cell
; 83(12): 1956-1958, 2023 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37327770
7.
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer.
Mol Cell
; 83(23): 4239-4254.e10, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38065062
8.
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Mol Cell
; 83(10): 1725-1742.e12, 2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084731
9.
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature
; 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720070
10.
ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1.
Mol Cell
; 82(13): 2443-2457.e7, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35613620
11.
Translating recent advances in the pathogenesis of acute myeloid leukemia to the clinic.
Genes Dev
; 36(5-6): 259-277, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35318270
12.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Mol Cell
; 81(10): 2183-2200.e13, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019788
13.
Emerging concepts of epigenetic dysregulation in hematological malignancies.
Nat Immunol
; 17(9): 1016-24, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27478938
14.
Recurrent SRSF2 mutations in MDS affect both splicing and NMD.
Genes Dev
; 34(5-6): 413-427, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001512
15.
Structural basis of cytokine-mediated activation of ALK family receptors.
Nature
; 600(7887): 143-147, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34646012
16.
The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.
Mol Cell
; 69(3): 412-425.e6, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29395063
17.
The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells.
Mol Cell
; 69(6): 923-937.e8, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29547721
18.
Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors.
N Engl J Med
; 386(8): 735-743, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35196427
19.
Efficacy of MEK inhibition in patients with histiocytic neoplasms.
Nature
; 567(7749): 521-524, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867592
20.
Spliceosomal disruption of the non-canonical BAF complex in cancer.
Nature
; 574(7778): 432-436, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31597964