Pesquisa | BVS IEC

1.

Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche.

Baldominos, Pilar; Barbera-Mourelle, Alex; Barreiro, Olga; Huang, Yu; Wight, Andrew; Cho, Jae-Won; Zhao, Xi; Estivill, Guillem; Adam, Isam; Sanchez, Xavier; McCarthy, Shannon; Schaller, Julien; Khan, Zara; Ruzo, Albert; Pastorello, Ricardo; Richardson, Edward T; Dillon, Deborah; Montero-Llopis, Paula; Barroso-Sousa, Romualdo; Forman, Juliet; Shukla, Sachet A; Tolaney, Sara M; Mittendorf, Elizabeth A; von Andrian, Ulrich H; Wucherpfennig, Kai W; Hemberg, Martin; Agudo, Judith.

Cell ; 185(10): 1694-1708.e19, 2022 05 12.

Artigo em Inglês | MEDLINE | ID: mdl-35447074

2.

Hair care: Stem cells control immune response during wound repair.

McCarthy, Shannon; Agudo, Judith.

Immunity ; 57(5): 933-935, 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38749394

3.

SOX17 enables immune evasion of early colorectal adenomas and cancers.

Goto, Norihiro; Westcott, Peter M K; Goto, Saori; Imada, Shinya; Taylor, Martin S; Eng, George; Braverman, Jonathan; Deshpande, Vikram; Jacks, Tyler; Agudo, Judith; Yilmaz, Ömer H.

Nature ; 627(8004): 636-645, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38418875

4.

Quiescent Tissue Stem Cells Evade Immune Surveillance.

Agudo, Judith; Park, Eun Sook; Rose, Samuel A; Alibo, Eziwoma; Sweeney, Robert; Dhainaut, Maxime; Kobayashi, Koichi S; Sachidanandam, Ravi; Baccarini, Alessia; Merad, Miriam; Brown, Brian D.

Immunity ; 48(2): 271-285.e5, 2018 02 20.

Artigo em Inglês | MEDLINE | ID: mdl-29466757

5.

The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.

Agudo, Judith; Ruzo, Albert; Tung, Navpreet; Salmon, Hélène; Leboeuf, Marylène; Hashimoto, Daigo; Becker, Christian; Garrett-Sinha, Lee-Ann; Baccarini, Alessia; Merad, Miriam; Brown, Brian D.

Nat Immunol ; 15(1): 54-62, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24270517

6.

Silence of the ROS.

Agudo, Judith; Brown, Brian D.

Immunity ; 44(3): 520-522, 2016 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-26982360

7.

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

Salmon, Hélène; Idoyaga, Juliana; Rahman, Adeeb; Leboeuf, Marylène; Remark, Romain; Jordan, Stefan; Casanova-Acebes, Maria; Khudoynazarova, Makhzuna; Agudo, Judith; Tung, Navpreet; Chakarov, Svetoslav; Rivera, Christina; Hogstad, Brandon; Bosenberg, Marcus; Hashimoto, Daigo; Gnjatic, Sacha; Bhardwaj, Nina; Palucka, Anna Karolina; Brown, Brian D; Brody, Joshua; Ginhoux, Florent; Merad, Miriam.

Immunity ; 44(4): 924-38, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-27096321

8.

Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.

Fiege, Jessica K; Stone, Ian A; Dumm, Rebekah E; Waring, Barbara M; Fife, Brian T; Agudo, Judith; Brown, Brian D; Heaton, Nicholas S; Langlois, Ryan A.

PLoS Pathog ; 15(9): e1008077, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31557273

9.

Immune privilege of skin stem cells: What do we know and what can we learn?

Agudo, Judith.

Exp Dermatol ; 30(4): 522-528, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33103270

10.

Insulin-like Growth Factor 2 Overexpression Induces ß-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage.

Casellas, Alba; Mallol, Cristina; Salavert, Ariana; Jimenez, Veronica; Garcia, Miquel; Agudo, Judith; Obach, Mercè; Haurigot, Virginia; Vilà, Laia; Molas, Maria; Lage, Ricardo; Morró, Meritxell; Casana, Estefania; Ruberte, Jesús; Bosch, Fatima.

J Biol Chem ; 290(27): 16772-85, 2015 Jul 03.

Artigo em Inglês | MEDLINE | ID: mdl-25971976

11.

A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade.

Agudo, Judith; Ruzo, Albert; Kitur, Kipyegon; Sachidanandam, Ravi; Blander, J Magarian; Brown, Brian D.

Mol Ther ; 20(12): 2257-67, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22871668

12.

Liver production of sulfamidase reverses peripheral and ameliorates CNS pathology in mucopolysaccharidosis IIIA mice.

Ruzo, Albert; Garcia, Miquel; Ribera, Albert; Villacampa, Pilar; Haurigot, Virginia; Marcó, Sara; Ayuso, Eduard; Anguela, Xavier M; Roca, Carles; Agudo, Judith; Ramos, David; Ruberte, Jesús; Bosch, Fatima.

Mol Ther ; 20(2): 254-66, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22008915

13.

Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation.

Trinh, Vincent Quoc-Huy; Lee, Ting-Fang; Lemoinne, Sara; Ray, Kevin C; Ybanez, Maria D; Tsuchida, Takuma; Carter, James K; Agudo, Judith; Brown, Brian D; Akat, Kemal M; Friedman, Scott L; Lee, Youngmin A.

Sci Signal ; 16(787): eadf6696, 2023 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-37253090

14.

Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer.

Hermida-Prado, Francisco; Xie, Yingtian; Sherman, Shira; Nagy, Zsuzsanna; Russo, Douglas; Akhshi, Tara; Chu, Zhengtao; Feit, Avery; Campisi, Marco; Chen, Minyue; Nardone, Agostina; Guarducci, Cristina; Lim, Klothilda; Font-Tello, Alba; Lee, Irene; García-Pedrero, Juana; Cañadas, Israel; Agudo, Judith; Huang, Ying; Sella, Tal; Jin, Qingchun; Tayob, Nabihah; Mittendorf, Elizabeth A; Tolaney, Sara M; Qiu, Xintao; Long, Henry; Symmans, William F; Lin, Jia-Ren; Santagata, Sandro; Bedrosian, Isabelle; Yardley, Denise A; Mayer, Ingrid A; Richardson, Edward T; Oliveira, Giacomo; Wu, Catherine J; Schuster, Eugene F; Dowsett, Mitch; Welm, Alana L; Barbie, David; Metzger, Otto; Jeselsohn, Rinath.

Cancer Res ; 83(19): 3284-3304, 2023 10 02.

Artigo em Inglês | MEDLINE | ID: mdl-37450351

15.

Protocol to isolate live single cells while retaining spatial information by combining cell photolabeling and FACS.

Baldominos, Pilar; Barreiro, Olga; von Andrian, Ulrich; Sirera, Rafael; Montero-Llopis, Paula; Agudo, Judith.

STAR Protoc ; 3(4): 101795, 2022 12 16.

Artigo em Inglês | MEDLINE | ID: mdl-36325581

16.

Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer.

Waks, Adrienne G; Keenan, Tanya E; Li, Tianyu; Tayob, Nabihah; Wulf, Gerburg M; Richardson, Edward T; Attaya, Victoria; Anderson, Leilani; Mittendorf, Elizabeth A; Overmoyer, Beth; Winer, Eric P; Krop, Ian E; Agudo, Judith; Van Allen, Eliezer M; Tolaney, Sara M.

J Immunother Cancer ; 10(10)2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36252998

17.

Introductions to the community: Early-career researchers in the time of COVID-19.

Agudo, Judith; Cheng, Chia-Wei; Jones, Courtney L; Avgustinova, Alexandra; Rodriguez-Fraticelli, Alejo E; Storer, Mekayla.

Cell Stem Cell ; 28(4): 600-602, 2021 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-33798421

18.

The Immunology of Hormone Receptor Positive Breast Cancer.

Goldberg, Jonathan; Pastorello, Ricardo G; Vallius, Tuulia; Davis, Janae; Cui, Yvonne Xiaoyong; Agudo, Judith; Waks, Adrienne G; Keenan, Tanya; McAllister, Sandra S; Tolaney, Sara M; Mittendorf, Elizabeth A; Guerriero, Jennifer L.

Front Immunol ; 12: 674192, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34135901

19.

Integrin αvß6-TGFß-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer.

Bagati, Archis; Kumar, Sushil; Jiang, Peng; Pyrdol, Jason; Zou, Angela E; Godicelj, Anze; Mathewson, Nathan D; Cartwright, Adam N R; Cejas, Paloma; Brown, Myles; Giobbie-Hurder, Anita; Dillon, Deborah; Agudo, Judith; Mittendorf, Elizabeth A; Liu, X Shirley; Wucherpfennig, Kai W.

Cancer Cell ; 39(1): 54-67.e9, 2021 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-33385331

20.

Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer.

Keenan, Tanya E; Guerriero, Jennifer L; Barroso-Sousa, Romualdo; Li, Tianyu; O'Meara, Tess; Giobbie-Hurder, Anita; Tayob, Nabihah; Hu, Jiani; Severgnini, Mariano; Agudo, Judith; Vaz-Luis, Ines; Anderson, Leilani; Attaya, Victoria; Park, Jihye; Conway, Jake; He, Meng Xiao; Reardon, Brendan; Shannon, Erin; Wulf, Gerburg; Spring, Laura M; Jeselsohn, Rinath; Krop, Ian; Lin, Nancy U; Partridge, Ann; Winer, Eric P; Mittendorf, Elizabeth A; Liu, David; Van Allen, Eliezer M; Tolaney, Sara M.

Nat Commun ; 12(1): 5563, 2021 09 21.

Artigo em Inglês | MEDLINE | ID: mdl-34548479

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Instituto Evandro Chagas

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