Detalhe da pesquisa
1.
Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference.
PLoS Pathog
; 16(12): e1009061, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33347499
2.
New live attenuated tuberculosis vaccine MTBVAC induces trained immunity and confers protection against experimental lethal pneumonia.
PLoS Pathog
; 16(4): e1008404, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32240273
3.
New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages.
PLoS Genet
; 14(4): e1007282, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29649213
4.
Evaluation of the immunogenicity and efficacy of BCG and MTBVAC vaccines using a natural transmission model of tuberculosis.
Vet Res
; 50(1): 82, 2019 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31615555
5.
Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17-Dependent Mechanism.
J Infect Dis
; 213(5): 831-9, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494773
6.
Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.
J Biol Chem
; 290(11): 6868-77, 2015 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605735
7.
Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes.
Cell Microbiol
; 17(11): 1537-60, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26045209
8.
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component.
Infect Immun
; 82(8): 3446-56, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24891105
9.
Mycobacterium tuberculosis infection prevents asthma and abrogates eosinophilopoiesis in an experimental model.
Allergy
; 74(12): 2512-2514, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31116888
10.
Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates.
Front Immunol
; 15: 1387454, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799468
11.
Heat-killed Mycobacterium tuberculosis induces trained immunity in vitro and in vivo administered systemically or intranasally.
iScience
; 27(2): 108869, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38318361
12.
BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded in vitro.
Oncoimmunology
; 12(1): 2160094, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36567803
13.
Intravenous administration of BCG in mice promotes natural killer and T cell-mediated antitumor immunity in the lung.
Nat Commun
; 14(1): 6090, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794033
14.
The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy.
Mol Ther Nucleic Acids
; 27: 1235-1248, 2022 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35282413
15.
Novel intravesical bacterial immunotherapy induces rejection of BCG-unresponsive established bladder tumors.
J Immunother Cancer
; 10(7)2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35781395
16.
MTBVAC, a live TB vaccine poised to initiate efficacy trials 100 years after BCG.
Vaccine
; 39(50): 7277-7285, 2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34238608
17.
Therapeutic efficacy of pulmonary live tuberculosis vaccines against established asthma by subverting local immune environment.
EBioMedicine
; 64: 103186, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33478923
18.
Natural Killer Anti-Tumor Activity Can Be Achieved by In Vitro Incubation With Heat-Killed BCG.
Front Immunol
; 12: 622995, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33708215
19.
BCG vaccination improves DTaP immune responses in mice and is associated with lower pertussis incidence in ecological epidemiological studies.
EBioMedicine
; 65: 103254, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33711798
20.
Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis.
Sci Immunol
; 6(63): eabc2934, 2021 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34559551