Detalhe da pesquisa
1.
Population Pharmacokinetic Properties of Omecamtiv Mecarbil in Healthy Subjects and Patients With Heart Failure With Reduced Ejection Fraction.
J Cardiovasc Pharmacol
; 79(4): 539-548, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34983909
2.
Performance of longitudinal item response theory models in shortened or partial assessments.
J Pharmacokinet Pharmacodyn
; 47(5): 461-471, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32617833
3.
Operating characteristics of stepwise covariate selection in pharmacometric modeling.
J Pharmacokinet Pharmacodyn
; 46(3): 273-285, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31020450
4.
Time dependent pharmacokinetics of pembrolizumab in patients with solid tumor and its correlation with best overall response.
J Pharmacokinet Pharmacodyn
; 44(5): 403-414, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28573468
5.
Methods and strategies for assessing uncontrolled drug-drug interactions in population pharmacokinetic analyses: results from the International Society of Pharmacometrics (ISOP) Working Group.
J Pharmacokinet Pharmacodyn
; 43(2): 123-35, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26837775
6.
Considerations for Industry-Preparing for the FDA Model-Informed Drug Development (MIDD) Paired Meeting Program.
Clin Pharmacol Ther
; 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38519861
7.
Covariate modeling in pharmacometrics: General points for consideration.
CPT Pharmacometrics Syst Pharmacol
; 13(5): 710-728, 2024 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38566433
8.
Oncolytic viral kinetics mechanistic modeling of Talimogene Laherparepvec (T-VEC) a first-in-class oncolytic viral therapy in patients with advanced melanoma.
CPT Pharmacometrics Syst Pharmacol
; 12(2): 250-260, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564918
9.
Evaluation of the effect of erenumab on migraine-specific questionnaire in patients with chronic and episodic migraine.
CPT Pharmacometrics Syst Pharmacol
; 12(12): 1988-2000, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37723849
10.
Recent advances and clinical pharmacology aspects of Chimeric Antigen Receptor (CAR) T-cellular therapy development.
Clin Transl Sci
; 15(9): 2057-2074, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35677992
11.
A Disease Progression Model to Quantify the Nonmotor Symptoms of Parkinson's Disease in Participants With Leucine-Rich Repeat Kinase 2 Mutation.
Clin Pharmacol Ther
; 110(2): 508-518, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33894056
12.
Population pharmacokinetics of orally administrated bromopride: Focus on the absorption process.
Eur J Pharm Sci
; 142: 105081, 2020 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31669384
13.
Challenges in Alzheimer's Disease Drug Discovery and Development: The Role of Modeling, Simulation, and Open Data.
Clin Pharmacol Ther
; 107(4): 796-805, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31955409
14.
Development of a Disease Progression Model for Leucine-Rich Repeat Kinase 2 in Parkinson's Disease to Inform Clinical Trial Designs.
Clin Pharmacol Ther
; 107(3): 553-562, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31544231
15.
Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease.
Clin Transl Sci
; 12(3): 240-246, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30706986
16.
Model-Informed Drug Development: Steps Toward Harmonized Guidance.
Clin Pharmacol Ther
; 114(5): 954-959, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37534711
17.
Evaluation of dosing strategy for pembrolizumab for oncology indications.
J Immunother Cancer
; 5: 43, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28515943
18.
Prediction of concentration-time profile and its inter-individual variability following the dermal drug absorption.
J Pharm Sci
; 101(7): 2584-95, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22517028