Detalhe da pesquisa
1.
Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy.
Mol Cell
; 81(24): 5082-5098.e11, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699746
2.
Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.
Mol Cell
; 70(2): 211-227.e8, 2018 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29656925
3.
Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity.
Mol Psychiatry
; 28(9): 3943-3954, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37914840
4.
Disease-specific induced pluripotent stem cells.
Cell
; 134(5): 877-86, 2008 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18691744
5.
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.
Nature
; 466(7307): 714-9, 2010 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20686566
6.
Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism.
bioRxiv
; 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38529501
7.
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.
Nat Commun
; 15(1): 447, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38200091
8.
Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson's disease.
Sci Adv
; 10(2): eadi8287, 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38198537
9.
Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity.
iScience
; 26(9): 107525, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37646018
10.
A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides.
Nat Commun
; 14(1): 2803, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37193692
11.
Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson's disease.
Stem Cell Res Ther
; 12(1): 253, 2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33926571
12.
High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells.
STAR Protoc
; 2(2): 100463, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33997803
13.
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells.
Nat Aging
; 1(9): 850-863, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35005630
14.
Modeling the complex genetic architectures of brain disease.
Nat Genet
; 52(4): 363-369, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32203467
15.
Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons.
Stem Cell Reports
; 14(1): 75-90, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31902706
16.
Publisher Correction: A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides.
Nat Commun
; 14(1): 3747, 2023 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37353544
17.
Studying human disease using human neurons.
Brain Res
; 1656: 40-48, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27060768
18.
A TALEN genome-editing system for generating human stem cell-based disease models.
Cell Stem Cell
; 12(2): 238-51, 2013 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23246482
19.
Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs.
Cell Stem Cell
; 10(4): 385-97, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22482504
20.
Programming human pluripotent stem cells into white and brown adipocytes.
Nat Cell Biol
; 14(2): 209-19, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22246346