Detalhe da pesquisa
1.
IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter.
Proc Natl Acad Sci U S A
; 119(33): e2121040119, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943986
2.
Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction.
Proc Natl Acad Sci U S A
; 114(36): 9731-9736, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827363
3.
The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons.
Brain
; 140(7): 2012-2027, 2017 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28595357
4.
Regulatory T cells delay disease progression in Alzheimer-like pathology.
Brain
; 139(Pt 4): 1237-51, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912648
5.
Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-ß Clearance.
J Neurosci
; 35(33): 11500-13, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26290229
6.
IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.
J Neurosci
; 35(34): 12063-79, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26311784
7.
Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.
J Neurochem
; 124(1): 59-68, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23083210
8.
Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.
J Neurochem
; 120(2): 292-301, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22050439
9.
The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research.
Trends Pharmacol Sci
; 30(4): 174-81, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19269697
10.
Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aß/amyloid burden in a transgenic mouse model of Alzheimer's disease.
J Neuroinflammation
; 7: 57, 2010 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20920207
11.
Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2.
J Neuroinflammation
; 5: 17, 2008 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18489773
12.
Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging.
Brain Res Bull
; 73(1-3): 108-13, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17499644
13.
Disrupting IGF Signaling in Adult Mice Conditions Leanness, Resilient Energy Metabolism, and High Growth Hormone Pulses.
Endocrinology
; 158(7): 2269-2283, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28881863
14.
Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.
J Cereb Blood Flow Metab
; 37(2): 396-412, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762506
15.
Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging.
Aging Cell
; 14(5): 847-56, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26219530
16.
Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications.
Biochimie
; 93(1): 46-51, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20868723
17.
Neuronal overexpression of cyclooxygenase-2 does not alter the neuroinflammatory response during brain innate immune activation.
Neurosci Lett
; 478(3): 113-8, 2010 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20451580
18.
Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity.
J Cereb Blood Flow Metab
; 30(2): 370-80, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19844242