Detalhe da pesquisa
1.
Identification of a γc Receptor Antagonist That Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21.
Gastroenterology
; 158(3): 625-637.e13, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31622625
2.
Correction: Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality.
PLoS Genet
; 13(4): e1006709, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28441397
3.
Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality.
PLoS Genet
; 11(7): e1005310, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132554
4.
A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity.
PLoS Pathog
; 10(4): e1004064, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24722365
5.
High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment.
J Virol
; 88(17): 10157-64, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24965464
6.
High-throughput profiling of point mutations across the HIV-1 genome.
Retrovirology
; 11: 124, 2014 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25522661
7.
Systematic identification of H274Y compensatory mutations in influenza A virus neuraminidase by high-throughput screening.
J Virol
; 87(2): 1193-9, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23152521
8.
Single-round, multiplexed antibody mimetic design through mRNA display.
Angew Chem Int Ed Engl
; 51(50): 12449-53, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23125174
9.
Are we living in the end of the blockbuster drug era?
Drug News Perspect
; 23(10): 670-84, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21180653
10.
Results From a First-in-Human Study of BNZ-1, a Selective Multicytokine Inhibitor Targeting Members of the Common Gamma (γc) Family of Cytokines.
J Clin Pharmacol
; 60(2): 264-273, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31465127
11.
Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy.
Trends Pharmacol Sci
; 28(10): 526-35, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17888520
12.
Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis.
FEBS Lett
; 582(10): 1425-30, 2008 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18331842
13.
Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors.
J Med Chem
; 51(5): 1136-44, 2008 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18281931
14.
Anti-infectives: clinical progress of HIV-1 integrase inhibitors.
Expert Opin Emerg Drugs
; 13(2): 213-25, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18537517
15.
Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity.
FEBS Lett
; 581(6): 1151-6, 2007 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-17328897
16.
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
Bioorg Med Chem Lett
; 17(23): 6472-5, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17950601
17.
HIV-1 integrase inhibitors: an emerging clinical reality.
Drugs R D
; 8(3): 155-68, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17472411
18.
From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes.
J Med Chem
; 49(14): 4248-60, 2006 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16821784
19.
Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing.
AIDS Res Hum Retroviruses
; 30(8): 806-11, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914638
20.
High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution.
Sci Rep
; 4: 4942, 2014 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24820965