[Seroprevalence of viral hepatitis B and its associated factors determined based on data from a screening campaign targeting the general population in Benin]. / Hépatite virale B lors d´une campagne de dépistage en population générale au Bénin: séroprévalence et facteurs associés.

INTRODUCTION: hepatitis B is a global public health problem. The purpose of this study was to determine the prevalence of hepatitis B virus (HBV) and its associated factors based on data from a mass screening in several localities across Benin. METHOD: we conducted a cross-sectional descriptive and analytical study with prospective data collection. Data collection was carried out during voluntary free hepatitis B screening organized by the Rotary Club in 23 localities across Benin from the 20th to 28th July 2019. Rapid test for diagnostic orientation was used for the detection of HBs antigen. RESULTS: a total of 9035 volunteers were included in the study. They were mostly of Benin origin (99%), with a mean age of 27 years; 51.1% of them were singles, mainly schoolchildren, pupils or students (37.9%). HBV seroprevalence was 6% (545/9035) [95%CI=5.5%-6.5%]. In univariate analysis, factors associated with HBs Ag colonization were: age, sex, marital status, education level, occupation and a history of diabetes, scarification and hepatitis C, while in multivariate analysis they were: sex, age and education level. CONCLUSION: HBV seroprevalence is 6% in the study population. HBV infection mainly affects male subjects over 17 years of age with secondary-level education.

[Seroprevalence and factors associated with viral hepatitis B among pregnant women in Parakou, Republic of Benin]. / Séroprévalence et facteurs associés à l'hépatite virale B chez les gestantes à Parakou en République du Bénin.

The purpose of this study is to determine the seroprevalence and the factors associated with viral hepatitis B among pregnant women at the Departmental University Hospital of Borgou (CHUD-B).We conducted a cross-sectional descriptive and analytical study with prospective collection of data. It focused on pregnant women treated and/or having given birth at the CHUD-B from 1 April 2017 to 30 June 2017. The study included patients who gave their consent to participate in the study. The variables studied were the sociodemographic data of pregnant women and the result of HBsAg test. The detectionof HBsAg in blood sampling of pregnant women was performed using a biological test for rapid diagnosis. Positive results were confirmed by ELISA technique. Two hundred and fourteen (214) pregnant women were included in the study. The average age of patients was 26.73±5.68 years. The mean gestation age was 31 weeks of amenorrhea (WA) ranging from 4 WA and 42 WA. Among them, 30 women were positive for HBsAg, reflecting a prevalence of 14.02%. The factors associated with this colonization were the practice of scarification, a personal history of jaundice and family history of viral hepatitis B. The seroprevalence of viral hepatitis B among pregnant women at the CHUD-B is high. This best reflect this major public health problem due to Hepatitis B virus.

[Impact of HIV status on the overall prevalence of chronic hepatitis B infection in Parakou, Benin]. / Prévalence de l'hépatite B chronique selon le statut sérologique VIH à Parakou au Bénin.

INTRODUCTION: The prevalence of hepatitis B is very variable across geographic areas and seems to be influenced by HIV infection. This study aims to evaluate the impact of serologic HIV status on the overall prevalence of hepatitis B in a Hospital in Parakou, Benin. METHODS: We conducted a cross-sectional study of adults aged 18 years old and over hospitalized in the Departmental University Hospital Center in Parakou between May 2011 and June 2012. The diagnosis of hepatitis B was made on the basis of rapid HBsAg tests while the diagnosis of HIV was made on the basis of rapid HIV tests using venous blood samples. Data were analyzed using EpiInfo software. Multivariate logistic regression model was implemented to investigate factors associated with hepatitis B. RESULTS: Out of 1516 subjects included, 744 were HIV seropositive. The average age was 31.3 + 11.1 years and 65.1% were women. The prevalence rate of hepatitis B in the whole sample was 13.9% [CI95:12.2%-15.7%]. This prevalence was higher in HIV seropositive subjects (16.9% vs 10.9%; p < 0.0006), however there was not a more significant difference in multivariate analysis, except for the group of subjects from Borgou/Alibori (p < 0.02). A consistent association was observed between age group 24-44 years (p < 0.03), male sex (p < 0.01), primary school education (p < 0.02) and a high prevalence of hepatitis B. CONCLUSION: The prevalence of hepatitis B was higher in HIV seropositive subjects. This was influenced by age, sex, education level and geographical origin.