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1.
Phys Rev Lett ; 132(19): 195001, 2024 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-38804956

RESUMO

Experiments were performed on laser wakefield acceleration in the highly nonlinear regime. With laser powers P<250 TW and using an initial spot size larger than the matched spot size for guiding, we were able to accelerate electrons to energies E_{max}>2.5 GeV, in fields exceeding 500 GV m^{-1}, with more than 80 pC of charge at energies E>1 GeV. Three-dimensional particle-in-cell simulations show that using an oversized spot delays injection, avoiding beam loss as the wakefield undergoes length oscillation. This enables injected electrons to remain in the regions of highest accelerating fields and leads to a doubling of energy gain as compared to results from using half the focal length with the same laser.

2.
Sci Rep ; 5: 13244, 2015 Aug 18.
Artigo em Inglês | MEDLINE | ID: mdl-26283308

RESUMO

A bright µm-sized source of hard synchrotron x-rays (critical energy Ecrit > 30 keV) based on the betatron oscillations of laser wakefield accelerated electrons has been developed. The potential of this source for medical imaging was demonstrated by performing micro-computed tomography of a human femoral trabecular bone sample, allowing full 3D reconstruction to a resolution below 50 µm. The use of a 1 cm long wakefield accelerator means that the length of the beamline (excluding the laser) is dominated by the x-ray imaging distances rather than the electron acceleration distances. The source possesses high peak brightness, which allows each image to be recorded with a single exposure and reduces the time required for a full tomographic scan. These properties make this an interesting laboratory source for many tomographic imaging applications.


Assuntos
Fêmur/diagnóstico por imagem , Imageamento Tridimensional/instrumentação , Lasers , Aceleradores de Partículas/instrumentação , Tomografia Computadorizada por Raios X/instrumentação , Absorciometria de Fóton/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Humanos , Aumento da Imagem/instrumentação , Técnicas In Vitro , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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