Pesquisa | BVS IEC

1.

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.

Tarallo, Valeria; Hirano, Yoshio; Gelfand, Bradley D; Dridi, Sami; Kerur, Nagaraj; Kim, Younghee; Cho, Won Gil; Kaneko, Hiroki; Fowler, Benjamin J; Bogdanovich, Sasha; Albuquerque, Romulo J C; Hauswirth, William W; Chiodo, Vince A; Kugel, Jennifer F; Goodrich, James A; Ponicsan, Steven L; Chaudhuri, Gautam; Murphy, Michael P; Dunaief, Joshua L; Ambati, Balamurali K; Ogura, Yuichiro; Yoo, Jae Wook; Lee, Dong-ki; Provost, Patrick; Hinton, David R; Núñez, Gabriel; Baffi, Judit Z; Kleinman, Mark E; Ambati, Jayakrishna.

Cell ; 149(4): 847-59, 2012 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-22541070

2.

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.

Kaneko, Hiroki; Dridi, Sami; Tarallo, Valeria; Gelfand, Bradley D; Fowler, Benjamin J; Cho, Won Gil; Kleinman, Mark E; Ponicsan, Steven L; Hauswirth, William W; Chiodo, Vince A; Karikó, Katalin; Yoo, Jae Wook; Lee, Dong-ki; Hadziahmetovic, Majda; Song, Ying; Misra, Smita; Chaudhuri, Gautam; Buaas, Frank W; Braun, Robert E; Hinton, David R; Zhang, Qing; Grossniklaus, Hans E; Provis, Jan M; Madigan, Michele C; Milam, Ann H; Justice, Nikki L; Albuquerque, Romulo J C; Blandford, Alexander D; Bogdanovich, Sasha; Hirano, Yoshio; Witta, Jassir; Fuchs, Elaine; Littman, Dan R; Ambati, Balamurali K; Rudin, Charles M; Chong, Mark M W; Provost, Patrick; Kugel, Jennifer F; Goodrich, James A; Dunaief, Joshua L; Baffi, Judit Z; Ambati, Jayakrishna.

Nature ; 471(7338): 325-30, 2011 Mar 17.

Artigo em Inglês | MEDLINE | ID: mdl-21297615

3.

The newest member of the VEGF family.

Albuquerque, Romulo J C.

Blood ; 121(20): 4015-6, 2013 May 16.

Artigo em Inglês | MEDLINE | ID: mdl-23682028

4.

CCR3 is a target for age-related macular degeneration diagnosis and therapy.

Takeda, Atsunobu; Baffi, Judit Z; Kleinman, Mark E; Cho, Won Gil; Nozaki, Miho; Yamada, Kiyoshi; Kaneko, Hiroki; Albuquerque, Romulo J C; Dridi, Sami; Saito, Kuniharu; Raisler, Brian J; Budd, Steven J; Geisen, Pete; Munitz, Ariel; Ambati, Balamurali K; Green, Martha G; Ishibashi, Tatsuro; Wright, John D; Humbles, Alison A; Gerard, Craig J; Ogura, Yuichiro; Pan, Yuzhen; Smith, Justine R; Grisanti, Salvatore; Hartnett, M Elizabeth; Rothenberg, Marc E; Ambati, Jayakrishna.

Nature ; 460(7252): 225-30, 2009 Jul 09.

Artigo em Inglês | MEDLINE | ID: mdl-19525930

5.

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.

Kleinman, Mark E; Yamada, Kiyoshi; Takeda, Atsunobu; Chandrasekaran, Vasu; Nozaki, Miho; Baffi, Judit Z; Albuquerque, Romulo J C; Yamasaki, Satoshi; Itaya, Masahiro; Pan, Yuzhen; Appukuttan, Binoy; Gibbs, Daniel; Yang, Zhenglin; Karikó, Katalin; Ambati, Balamurali K; Wilgus, Traci A; DiPietro, Luisa A; Sakurai, Eiji; Zhang, Kang; Smith, Justine R; Taylor, Ethan W; Ambati, Jayakrishna.

Nature ; 452(7187): 591-7, 2008 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-18368052

6.

Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.

Kleinman, Mark E; Kaneko, Hiroki; Cho, Won Gil; Dridi, Sami; Fowler, Benjamin J; Blandford, Alexander D; Albuquerque, Romulo J C; Hirano, Yoshio; Terasaki, Hiroko; Kondo, Mineo; Fujita, Takashi; Ambati, Balamurali K; Tarallo, Valeria; Gelfand, Bradley D; Bogdanovich, Sasha; Baffi, Judit Z; Ambati, Jayakrishna.

Mol Ther ; 20(1): 101-8, 2012 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-21988875

7.

Corneal avascularity is due to soluble VEGF receptor-1.

Ambati, Balamurali K; Nozaki, Miho; Singh, Nirbhai; Takeda, Atsunobu; Jani, Pooja D; Suthar, Tushar; Albuquerque, Romulo J C; Richter, Elizabeth; Sakurai, Eiji; Newcomb, Michael T; Kleinman, Mark E; Caldwell, Ruth B; Lin, Qing; Ogura, Yuichiro; Orecchia, Angela; Samuelson, Don A; Agnew, Dalen W; St Leger, Judy; Green, W Richard; Mahasreshti, Parameshwar J; Curiel, David T; Kwan, Donna; Marsh, Helene; Ikeda, Sakae; Leiper, Lucy J; Collinson, J Martin; Bogdanovich, Sasha; Khurana, Tejvir S; Shibuya, Masabumi; Baldwin, Megan E; Ferrara, Napoleone; Gerber, Hans-Peter; De Falco, Sandro; Witta, Jassir; Baffi, Judit Z; Raisler, Brian J; Ambati, Jayakrishna.

Nature ; 443(7114): 993-7, 2006 Oct 26.

Artigo em Inglês | MEDLINE | ID: mdl-17051153

8.

Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth.

Cho, Won Gil; Albuquerque, Romulo J C; Kleinman, Mark E; Tarallo, Valeria; Greco, Adelaide; Nozaki, Miho; Green, Martha G; Baffi, Judit Z; Ambati, Balamurali K; De Falco, Massimo; Alexander, Jonathan S; Brunetti, Arturo; De Falco, Sandro; Ambati, Jayakrishna.

Proc Natl Acad Sci U S A ; 106(17): 7137-42, 2009 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-19359485

9.

The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model.

Shibata, Masa-Aki; Ambati, Jayakrishna; Shibata, Eiko; Albuquerque, Romulo J C; Morimoto, Junji; Ito, Yuko; Otsuki, Yoshinori.

BMC Med ; 8: 69, 2010 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-21047425

10.

Latent Sensitization in a Mouse Model of Ocular Neuropathic Pain.

Cho, Jooyoung; Bell, Nicholas; Botzet, Gregory; Vora, Paras; Fowler, Benjamin J; Donahue, Renee; Bush, Heather; Taylor, Bradley K; Albuquerque, Romulo J C.

Transl Vis Sci Technol ; 8(2): 6, 2019 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-30937216

11.

Are female patients with orofacial pain medically compromised?

de Leeuw, Reny; Klasser, Gary D; Albuquerque, Romulo J C.

J Am Dent Assoc ; 136(4): 459-68, 2005 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-15884315

12.

Self-report health questionnaire: a necessary and reliable tool in dentistry.

Klasser, Gary D; de Leeuw, Reny; Albuquerque, Romulo J C.

Gen Dent ; 53(5): 348-54; quiz 355, 367-8, 2005.

Artigo em Inglês | MEDLINE | ID: mdl-16252539

13.

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.

Albuquerque, Romulo J C; Hayashi, Takahiko; Cho, Won Gil; Kleinman, Mark E; Dridi, Sami; Takeda, Atsunobu; Baffi, Judit Z; Yamada, Kiyoshi; Kaneko, Hiroki; Green, Martha G; Chappell, Joe; Wilting, Jörg; Weich, Herbert A; Yamagami, Satoru; Amano, Shiro; Mizuki, Nobuhisa; Alexander, Jonathan S; Peterson, Martha L; Brekken, Rolf A; Hirashima, Masanori; Capoor, Seema; Usui, Tomohiko; Ambati, Balamurali K; Ambati, Jayakrishna.

Nat Med ; 15(9): 1023-30, 2009 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-19668192

14.

Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1.

Ponticelli, Salvatore; Marasco, Daniela; Tarallo, Valeria; Albuquerque, Romulo J C; Mitola, Stefania; Takeda, Atsunobu; Stassen, Jean-Marie; Presta, Marco; Ambati, Jayakrishna; Ruvo, Menotti; De Falco, Sandro.

J Biol Chem ; 283(49): 34250-9, 2008 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-18922791

15.

Influence of estrogen on brain activation during stimulation with painful heat.

de Leeuw, Reny; Albuquerque, Romulo J C; Andersen, Anders H; Carlson, Charles R.

J Oral Maxillofac Surg ; 64(2): 158-66, 2006 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-16413884

16.

Cerebral activation during thermal stimulation of patients who have burning mouth disorder: an fMRI study.

Albuquerque, Romulo J C; de Leeuw, Reny; Carlson, Charles R; Okeson, Jeffrey P; Miller, Craig S; Andersen, Anders H.

Pain ; 122(3): 223-234, 2006 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16632202

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Instituto Evandro Chagas

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