Factors associated with vaccine adherence among an underserved population: the adult Travellers in Nouvelle-Aquitaine, France.

BACKGROUND: A measles epidemic affected the Nouvelle-Aquitaine region from November 2017 to May 2018 with clusters among Travellers. This indicates that measles vaccination rates among Travellers remain lower than in the general population. The objective of this study was to estimate the 'declarative vaccination' against measles, mumps and rubella (MMR) and to propose a conceptual framework to help identify determinants of MMR vaccination uptake among adult Travellers in Nouvelle-Aquitaine in 2019-20. METHODS: A cross-sectional study using random sampling was performed and included 612 adult Travellers from 1 November 2019 to 31 March 2020. A conceptual framework to model vaccination adherence was tested among this underserved population by using structural equation modelling. This model included five latent variables: health literacy, attitudes toward preventive measures, stigma, accessibility to care and perceived needs and five measured variables: information received on vaccination, perception of barriers, support for administrative documents, social support and housing conditions. RESULTS: Individuals who did not answer all the questions linked to the variables included in the model were excluded, thus 347 adults were included in the final sample. The declared vaccination rate against MMR was 74.0%, and 72.4% of the participants were favorable to vaccination. Vaccination adherence was significantly correlated with favorable attitudes toward preventive measures such as having a history of MMR vaccination and not having already refused a recommended vaccine and finally satisfactory information received on vaccination. DISCUSSION: To improve vaccination adherence, health authorities should lean on personal history with vaccination and on transmitting information on vaccination.

Littératie en santé et prévention du cancer.

In recent years, there has been a noticeable drop in mortality rates from cancer, although cancer remains the primary cause of death in France and in the province of Québec. Several factors contribute to this reduction in mortality rates.First, better cancer screening is provided, and better follow ups are offered when abnormalities are detected. Second, cancer treatments benefit from ongoing developments which provide new treatments and more efficient measures to fight this illness. Last, we must also credit promotional campaigns to adopt healthy habits and lifestyles, particularly the fight against smoking.However, cancer strikes preferentially in some subgroups. In particular, cancer rates are higher and cancer-screening rates are lower in some subgroups, increasing disparities amongst subgroups of the same population. It seems that an insufficient level of literacy could be a factor explaining these discrepancies.This article presents a brief definition of the concept of literacy in general, followed by a definition of health-literacy behaviors and competencies. Then, we will present some data from research and from literature reviews on the potential linkages between literacy and cancer in general, and specific cancers in particular. We will conclude by considering a path to literacy in cancer screening.

[Health literacy and cancer screening] / Littératie en santé et prévention du cancer.

In recent years, there has been a noticeable drop in mortality rates from cancer, although cancer remains the primary cause of death in France and in the province of Québec. Several factors contribute to this reduction in mortality rates.First, better cancer screening is provided, and better follow ups are offered when abnormalities are detected. Second, cancer treatments benefit from ongoing developments which provide new treatments and more efficient measures to fight this illness. Last, we must also credit promotional campaigns to adopt healthy habits and lifestyles, particularly the fight against smoking.However, cancer strikes preferentially in some subgroups. In particular, cancer rates are higher and cancer-screening rates are lower in some subgroups, increasing disparities amongst subgroups of the same population. It seems that an insufficient level of literacy could be a factor explaining these discrepancies.This article presents a brief definition of the concept of literacy in general, followed by a definition of health-literacy behaviors and competencies. Then, we will present some data from research and from literature reviews on the potential linkages between literacy and cancer in general, and specific cancers in particular. We will conclude by considering a path to literacy in cancer screening.

A conceptual framework to model social determinants of COVID-19 vaccination uptake among underserved homeless populations.

Background:  Homeless people have a higher risk of COVID-19 infection, linked to several social, economic and environmental determinants, frequent comorbidities, obstacles to exercising their constitutional social and health rights, poor medical cover, and insufficient use of the healthcare system. Data on COVID-19 vaccine uptake and its main determinants are lacking for this underserved population. Objectives:  To construct and test a conceptual framework to model structural social determinants of COVID-19 vaccine uptake among underserved homeless populations, and to test this model to identify the determinants of COVID-19 vaccine uptake on the homeless population living in two metropolitan areas in France. Methods:  We implemented a multicenter cross-sectional survey from 15/11/2021 to 22/12/2021 in homeless adults in the city of Marseille and in the greater Paris area. Persons sheltered in migrant worker hostels or in emergency social shelters, members of the COVID HOMELESS cohort study in Marseille, and Travelers living in traditional housing were all eligible. A standardized face-to-face questionnaire was administered to the participants where they lived in various languages by trained interviewers. We used structural equation modeling to analyze the structural social determinants of COVID-19 vaccine uptake, the latter defined as receiving at least one dose. Results:  The participation rate was 64 %, accounting for 3811 participants. There were three main factors associated with greater vaccine uptake: i) opportunity, which included having a personal general practitioner (ß = 0.05, p < 0.05), healthcare cover (ß = 0.05, p < 0.05), and somebody to accompany the participant for medical appointments (ß = -0.04, p < 0.05); ii) motivation, which included attitudes towards vaccination (ß = 0.55, p < 0.05), press- and poster-based information (ß = 0.03, p < 0.05), and vaccination history (ß = 0.03, p < 0.05); iii) type of housing (ß = 0.13, p < 0.05) and housing stability (ß = 0.04, p < 0.05). Conclusion:  Our results highlight that housing exclusion is a structural social determinant of COVID-19 vaccine uptake in homeless people in France. They also underline the role which opportunity and motivation play in improving uptake in this underserved homeless population.

Health Literacy as a Mediator of the Relationship Between Socioeconomic Position and Pre-Exposure Prophylaxis Uptake Among Men Who Have Sex with Men Living in France.

BACKGROUND: In recent decades, several research studies have mentioned a potential mediating effect of health literacy (HL) on the relationship between socioeconomic position and health prevention behaviors. However, no study to date has investigated this hypothesis on HIV prevention behaviors. OBJECTIVE: The present study aimed to evaluate whether HL mediates the relationship between socioeconomic status (SES) and pre-exposure prophylaxis (PrEP) uptake in men who have sex with men (MSM). METHODS: The study is based on data collected in the Enquête Rapport au Sexe [report to sex] 2019 survey, an anonymous, self-administered online cross-sectional survey in France conducted between February 16, 2019 and March 31, 2019. Data on education level and perceived financial situation were used as measures of SES, whereas HL was assessed from the Health Literacy Questionnaire's "ability to actively engage with health care providers" scale. Mediation analyses were performed with a model-based causal moderated mediation analysis package in R software. Analyses were adjusted for age, place of residence, marital status, and social support. KEY RESULTS: The study sample included 13,629 MSM. Median age was 32 years. The majority had an education level higher than upper secondary school (78%) and an adequate HL level (73%). Almost two-thirds perceived their financial situation as comfortable (62%). Overall, PrEP uptake was low (9.5%). The analyses did not show a mediating effect of HL on the relationship between education and PrEP uptake. However, a total mediation effect of HL was observed on the relationship between perceived financial situation and uptake. CONCLUSIONS: In the context of PrEP uptake, MSM ability to actively engage with health care providers may offset the effect of a difficult financial situation. In the current French context, where PrEP is now also available in general practitioner settings, this result could inform the development of training and support policies for health professionals and the way in which sexual health issues are addressed in consultations. [HLRP: Health Literacy Research and Practice. 2023;7(1):e61-e70.].

Health Literacy throughout adolescence: Invariance and validity study of three measurement scales in the general population.

OBJECTIVE: To simultaneously investigate the psychometric properties of three recently developed health literacy measurement scales throughout adolescence in the general population. METHODS: French versions of the Health Literacy for School-Aged Children (HLSAC, unidimensional) scale, the Health Literacy Assessment Scale for Adolescents (HAS-A, multidimensional) and the 16-item European Health Literacy Survey questionnaire (HLS-EU-Q16, unidimensional) were completed by 1 444 adolescents in 8th, 9th, 11th grade in general school and 11-12th grade in vocational school. Psychometric properties were studied using confirmatory factor analysis, McDonald's omega coefficient and hypothesis testing. RESULTS: Structural validity was acceptable (HLS-EU-Q16) to good (HAS-A and HLSAC), no measurement invariance issue was found and internal consistency was acceptable for the three scales (0.68-0.84). Convergent validity was low (Pearson correlation coefficients<0.5) and the only scale for which results were in agreement with a priori hypotheses was the HLSAC. CONCLUSIONS: Our results were supportive of the use of HLSAC to assess health literacy during adolescence but the HAS-A, with a slightly better structural validity, can also be promoted due to its three measured dimensions. PRACTICE IMPLICATIONS: The use of these scales in practice will help to focus on health literacy, a critical factor for prevention and health promotion in adolescence.

Depression during the COVID-19 pandemic amongst residents of homeless shelters in France.

BACKGROUND: Accumulating evidence suggests that the COVID-19 pandemic has negatively affected global mental health and well-being. However, the impact amongst homeless persons has not been fully evaluated. The ECHO study reports factors associated with depression amongst the homeless population living in shelters in France during the spring of 2020. METHODS: Interview data were collected from 527 participants living in temporary and/or emergency accommodation following France's first lockdown (02/05/20 - 07/06/20), in the metropolitan regions of Paris (74%), Lyon (19%) and Strasbourg (7%). Interviews were conducted in French, English, or with interpreters (33% of participants, ∼20 languages). Presence of depression was ascertained using the Patient Health Questionnaire (PHQ-9). RESULTS: Amongst ECHO study participants, 30% had symptoms of moderate to severe depression (PHQ-9 ≥ 10). Multivariate analysis revealed depression to be associated with being female (aOR: 2.15; CI: 1.26-3.69), single (aOR: 1.60; CI: 1.01-2.52), chronically ill (aOR: 2.32; CI: 1.43: 3.78), facing food insecurity (aOR: 2.12; CI: 1.40-3.22) and participants' region of origin. Persons born African and Eastern Mediterranean regions showed higher levels of depression (30-33% of participants) than those migrating from other European countries (14%). Reduced rates of depression were observed amongst participants aged 30-49 (aOR: 0.60; CI: 0.38-0.95) and over 50 (aOR: 0.28; CI: 0.13-0.64), compared to 18-29-year-olds. LIMITATIONS: These data are cross-sectional, only providing information on a given moment in time. CONCLUSIONS: Our results indicate high levels of depression amongst homeless persons during the COVID-19 pandemic. Predicted future instability and economic repercussions could particularly impact the mental health of this vulnerable group.