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1.
IEEE Trans Biomed Eng ; 68(9): 2880-2891, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34043503

RESUMO

The timely treatment is the crucial element for the survival of patients with brain stroke. Thus, a fast, cost-effective, and portable device is needed for the early and on-the-spot diagnosis of stroke patients. A 3D electromagnetic head imaging system for rapid brain stroke diagnosis with a wearable and lightweight platform is presented. The platform comprises a custom-built flexible cap with a 24-element planar antenna array, and a flexible matching medium layer. The custom-built cap is made out of an engineered polymer-ceramic composite substrate of RTV silicone rubber and aluminum oxide (Al2O3) for enhanced dielectric properties and mechanical flexibility and robustness. The array is arranged into two elliptical rings that are entirely incorporated into the flexible cap. The employed antenna elements within the system are compact with low SAR values over the utilized frequency range of 0.9-2.5 GHz. Moreover, a flexible matching medium layer is introduced on the front of the apertures of the antenna array to enhance the impedance matching with the skin. The detection capability of the system is experimentally verified on 3D realistic head phantoms at multiple imaging scenarios and different types of strokes. The reconstructed 3D and 2D multi-slice images using the beamforming and polar sensitivity encoding (PSE) image processing algorithms indicate the applicability and potential of the system for onsite brain imaging.


Assuntos
Cabeça , Processamento de Imagem Assistida por Computador , Fenômenos Eletromagnéticos , Cabeça/diagnóstico por imagem , Humanos , Imageamento Tridimensional , Imagens de Fantasmas
2.
IEEE Trans Biomed Circuits Syst ; 14(5): 1097-1107, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32956066

RESUMO

A wideband wearable electromagnetic (EM) head imaging system for brain stroke detection is presented. The proposed system aims at overcoming the challenges of size, rigidity, and complex structures of existing systems. The proposed system is built into a light-weight and compact imaging platform, which integrates a 16-element antenna array into a highly flexible custom-made wearable cap made of a cost-effective and robust room-temperature-vulcanizing (RTV) silicone. The system mitigates the mismatch between the skin and antenna array by introducing a flexible high-permittivity matching layer. The utilized compact antenna demonstrates wideband operational frequency over 0.6-2.5 GHz with a low signal distortion, safe values of SAR, and unidirectional radiations. The system is experimentally validated on realistic head phantoms. The polar sensitivity encoding (PSE) image processing algorithm is utilized to generate 2D images of different testing scenarios. The obtained images of a stroke-like target inside the head phantoms demonstrate the merits and feasibility of the system for preclinical trials.


Assuntos
Diagnóstico por Imagem , Cabeça , Fenômenos Eletromagnéticos , Cabeça/diagnóstico por imagem , Micro-Ondas , Imagens de Fantasmas
3.
IEEE Trans Biomed Circuits Syst ; 13(1): 124-134, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30369449

RESUMO

Given the increased interest in a fast, portable, and on-spot medical diagnostic tool that enables early diagnosis for patients with brain stroke, a new approach of a wearable electromagnetic head imaging system based on the polymer material is proposed. A flexible low-profile, wideband, and unidirectional antenna array with electromagnetic band gap (EBG) and metamaterial (MTM) unit cells reflector is utilized. The designed antenna consists of a 4 × 4 radiating patch loaded with symmetrical extended open-ended U-slots and fed by combination of series and corporate transmission lines. A mushroom-like 10-EBG unit cell arrays are arranged around the feeding network to reduce surface waves, whereas 4 × 4 MTM unit cells are placed on the back-side of the antenna to enable unidirectional radiation. The antenna is designed and embedded on a multilayer low cost, low loss, transparent, and robust polymer poly-di-methyl-siloxane (PDMS) substrate and optimized to operate in contact with the human head. The simulated and measured results show that the antenna has a fractional bandwidth of 53.8% (1.16-1.94 GHz), more than 80% of radiation efficiency, and satisfactory field penetration in the head tissues with a safe specific absorption rate. An eight-element array is then configured on 300 × 360 × 4.1 mm3 PDMS material covering an average human head size and used as a worn part of the imaging system. A realistic-shaped 3-D specific anthropomorphic mannequin (SAM) head phantom is used to verify the performance of the designed array. The imaging results indicate the possibility of using the designed conformal array to detect a bleeding inside the brain using a confocal image algorithm.


Assuntos
Encéfalo/patologia , Radiação Eletromagnética , Imagens de Fantasmas , Acidente Vascular Cerebral/diagnóstico , Dispositivos Eletrônicos Vestíveis , Simulação por Computador , Cabeça , Humanos , Imageamento Tridimensional , Imageamento por Ressonância Magnética , Micro-Ondas , Análise Numérica Assistida por Computador , Polímeros , Reprodutibilidade dos Testes
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