Detalhe da pesquisa
1.
Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer's disease.
J Neuroinflammation
; 18(1): 273, 2021 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801055
2.
Azaindole therapeutic agents.
Bioorg Med Chem
; 28(24): 115830, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33161343
3.
Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties.
Mol Pharm
; 15(12): 5809-5817, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30398879
4.
Novel NADPH Oxidase-2 Inhibitors as Potential Anti-Inflammatory and Neuroprotective Agents.
Antioxidants (Basel)
; 12(9)2023 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759963
5.
Temporal Expression of Neuroinflammatory and Oxidative Stress Markers and Prostaglandin E2 Receptor EP2 Antagonist Effect in a Rat Model of Epileptogenesis.
ACS Pharmacol Transl Sci
; 6(1): 128-138, 2023 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36654746
6.
Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection.
bioRxiv
; 2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214943
7.
Preclinical development of an EP2 antagonist for post-seizure cognitive deficits.
Neuropharmacology
; 224: 109356, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460083
8.
Pharmacological antagonism of EP2 receptor does not modify basal cardiovascular and respiratory function, blood cell counts, and bone morphology in animal models.
Biomed Pharmacother
; 147: 112646, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091236
9.
Second-Generation Prostaglandin Receptor EP2 Antagonist, TG8-260, with High Potency, Selectivity, Oral Bioavailability, and Anti-Inflammatory Properties.
ACS Pharmacol Transl Sci
; 5(2): 118-133, 2022 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35187419
10.
A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats.
Neurotherapeutics
; 18(2): 1207-1225, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33410110
11.
An Agonist Dependent Allosteric Antagonist of Prostaglandin EP2 Receptors.
ACS Chem Neurosci
; 11(10): 1436-1446, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32324375
12.
Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models.
J Med Chem
; 63(3): 1032-1050, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31904232
13.
Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition.
Front Pharmacol
; 8: 406, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28713267