Detalhe da pesquisa
1.
Determination of pharmacological inhibition of ALDH2 by ethanol clearance in mice.
Toxicol Appl Pharmacol
; 483: 116801, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38181938
2.
Relevance of Human Aldoketoreductases and Microbial ß-Glucuronidases in Testosterone Disposition.
Drug Metab Dispos
; 51(4): 427-435, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36623880
3.
The world needs better male contraceptives: What is taking so long?
FASEB J
; 36(12): e22658, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36370122
4.
Isotretinoin and its Metabolites Alter mRNA of Multiple Enzyme and Transporter Genes In Vitro, but Downregulation of Organic Anion Transporting Polypeptide Does Not Translate to the Clinic.
Drug Metab Dispos
; 50(7): 1042-1052, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545255
5.
Dimethandrolone, a Potential Male Contraceptive Pill, is Primarily Metabolized by the Highly Polymorphic UDP-Glucuronosyltransferase 2B17 Enzyme in Human Intestine and Liver.
Drug Metab Dispos
; 50(12): 1493-1500, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36184078
6.
Two-Year Analysis of a New Oral Testosterone Undecanoate (TU) Formulation in Hypogonadal Men: Efficacy, Impact on Psychosexual Function, and Safety.
J Sex Med
; 19(12): 1750-1758, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36272969
7.
Investigation of an ALDH1A1-specific inhibitor for suppression of weight gain in a diet-induced mouse model of obesity.
Int J Obes (Lond)
; 45(7): 1542-1552, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33934107
8.
Longitudinal changes in plasma sex hormone concentrations correlate with changes in CT-measured regional adiposity among Japanese American men over 10 years.
Clin Endocrinol (Oxf)
; 93(5): 555-563, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32633813
9.
Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex.
Drug Metab Dispos
; 46(6): 888-896, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29602798
10.
Circulating sex steroids coregulate adipose tissue immune cell populations in healthy men.
Am J Physiol Endocrinol Metab
; 313(5): E528-E539, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28698282
11.
Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions.
J Pharmacol Exp Ther
; 361(2): 246-258, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275201
12.
Dose-response effects of sex hormone concentrations on body composition and adipokines in medically castrated healthy men administered graded doses of testosterone gel.
Clin Endocrinol (Oxf)
; 87(1): 59-67, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28370068
13.
Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations.
J Lipid Res
; 56(2): 342-57, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25502770
14.
Inhibition of retinoic acid biosynthesis by the bisdichloroacetyldiamine WIN 18,446 markedly suppresses spermatogenesis and alters retinoid metabolism in mice.
J Biol Chem
; 289(21): 15104-17, 2014 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711451
15.
The association of obesity with sex hormone-binding globulin is stronger than the association with ageing--implications for the interpretation of total testosterone measurements.
Clin Endocrinol (Oxf)
; 83(6): 828-33, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25777143
16.
Emerging approaches to male contraception.
Andrology
; 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38716676
17.
Shared risk and shared responsibility: the ethics of male contraceptives.
Andrology
; 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38639014
18.
Return to fertility, toxicology, and transgenerational impact of treatment with WIN 18,446, a potential male contraceptive, in mice.
Contraception
; 129: 110306, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37813273
19.
Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets.
bioRxiv
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798664
20.
Turning a spermatogenic wave into a tsunami: synchronizing murine spermatogenesis using WIN 18,446.
Biol Reprod
; 88(2): 40, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23284139