RESUMO
Dermatophytosis in children caused by Trichophyton rubrum is preferably treated with topical or systemic terbinafine. We report the first case of terbinafine resistance in a child with recurrent T. rubrum dermatophytosis and congenital ichthyosiform erythroderma.
Assuntos
Antifúngicos/uso terapêutico , Eritrodermia Ictiosiforme Congênita/complicações , Naftalenos/uso terapêutico , Tinha/tratamento farmacológico , Trichophyton/efeitos dos fármacos , Criança , Farmacorresistência Fúngica , Humanos , Itraconazol/uso terapêutico , Masculino , Recidiva , Terbinafina , Tinha/complicações , Trichophyton/isolamento & purificaçãoRESUMO
Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease with a growing health concern, because of its high prevalence and associated low quality of life. The etiology of AD is multifactorial with interaction between various factors such as genetic predisposition, immune, and importantly, environmental factors. Since climate change is associated with a profound shift in environmental factors, we suggest that AD is being influenced by climate change. This review highlights the effects of ultraviolet light, temperature, humidity, pollens, air pollutants, and their interaction between them contributing to the epidemiology and pathophysiology of AD.