Detalhe da pesquisa
1.
Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev
; 29(17): 1795-800, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26341557
2.
Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res
; 46(1): 421-430, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29145630
3.
Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis.
Proc Natl Acad Sci U S A
; 114(7): E1072-E1080, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137841
4.
Insights into newly discovered marks and readers of epigenetic information.
Nat Chem Biol
; 12(9): 662-8, 2016 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27538025
5.
The Taf14 YEATS domain is a reader of histone crotonylation.
Nat Chem Biol
; 12(6): 396-8, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27089029
6.
Chromatin condensation and recruitment of PHD finger proteins to histone H3K4me3 are mutually exclusive.
Nucleic Acids Res
; 44(13): 6102-12, 2016 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27016734
7.
Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Nucleic Acids Res
; 44(1): 472-84, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26626149
8.
Phosphonodifluoropyruvate is a mechanism-based inhibitor of phosphonopyruvate decarboxylase from Bacteroides fragilis.
Bioorg Med Chem
; 25(16): 4368-4374, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28693916
9.
The kinetic characterization and X-ray structure of a putative benzoylformate decarboxylase from M. smegmatis highlights the difficulties in the functional annotation of ThDP-dependent enzymes.
Biochim Biophys Acta
; 1854(8): 1001-9, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25936776
10.
Identification of charge transfer transitions related to thiamin-bound intermediates on enzymes provides a plethora of signatures useful in mechanistic studies.
Biochemistry
; 53(13): 2145-52, 2014 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24628377
11.
Perturbation of the monomer-monomer interfaces of the benzoylformate decarboxylase tetramer.
Biochemistry
; 53(27): 4358-67, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24956165
12.
A bulky hydrophobic residue is not required to maintain the V-conformation of enzyme-bound thiamin diphosphate.
Biochemistry
; 52(18): 3028-30, 2013 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23607689
13.
Substrate specificity in thiamin diphosphate-dependent decarboxylases.
Bioorg Chem
; 43: 26-36, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22245019
14.
Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun
; 9(1): 4574, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30385749
15.
Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J Mol Biol
; 429(13): 2066-2074, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697561
16.
Recognition of Histone H3K14 Acylation by MORF.
Structure
; 25(4): 650-654.e2, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28286003
17.
YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun
; 8(1): 1088, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057918
18.
The essential role of acetyllysine binding by the YEATS domain in transcriptional regulation.
Transcription
; 7(1): 14-20, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26934307
19.
Regulation of Methyllysine Readers through Phosphorylation.
ACS Chem Biol
; 11(3): 547-53, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26726824
20.
Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep
; 16(12): 3195-3207, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27653685