Detalhe da pesquisa
1.
Diverse alterations associated with resistance to KRAS(G12C) inhibition.
Nature
; 599(7886): 679-683, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34759319
2.
Acquired Resistance to KRASG12C Inhibition in Cancer.
N Engl J Med
; 384(25): 2382-2393, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161704
3.
Outcomes of Combination Platinum-Doublet Chemotherapy and Anti-PD(L)-1 Blockade in KRASG12C-Mutant Non-Small Cell Lung Cancer.
Oncologist
; 28(11): 978-985, 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37589215
4.
Systemic Therapy for Locally Advanced and Metastatic Non-Small Cell Lung Cancer: A Review.
JAMA
; 322(8): 764-774, 2019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31454018
5.
Twice weekly pulse and daily continuous-dose erlotinib as initial treatment for patients with epidermal growth factor receptor-mutant lung cancers and brain metastases.
Cancer
; 124(1): 105-109, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28940498
6.
Changing the Therapeutic Landscape in Non-small Cell Lung Cancers: the Evolution of Comprehensive Molecular Profiling Improves Access to Therapy.
Curr Oncol Rep
; 19(4): 24, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28303491
7.
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.
Cancer Discov
; : OF1-OF24, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593348
8.
Improving therapy for patients with epidermal growth factor receptor-mutant lung cancer.
Cancer
; 124(11): 2272-2275, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29645085
9.
Clinical and Genomic Features of Response and Toxicity to Sotorasib in a Real-World Cohort of Patients With Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer.
JCO Precis Oncol
; 7: e2300030, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384866
10.
The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non-Small Cell Lung Cancer.
Clin Cancer Res
; 29(17): 3418-3428, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37223888
11.
MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer.
Cancer Discov
; 13(11): 2412-2431, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552839
12.
Phase 1 Clinical Trial of Trametinib and Ponatinib in Patients With NSCLC Harboring KRAS Mutations.
JTO Clin Res Rep
; 3(1): 100256, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34984405
13.
Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers.
Cancer Res
; 82(21): 4058-4078, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36074020
14.
Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status.
J Thorac Oncol
; 17(3): 399-410, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34740862
15.
Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer.
Nat Med
; 28(11): 2353-2363, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36357680
16.
Treatment Outcomes and Clinical Characteristics of Patients with KRAS-G12C-Mutant Non-Small Cell Lung Cancer.
Clin Cancer Res
; 27(8): 2209-2215, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33558425
17.
Deep Learning to Estimate RECIST in Patients with NSCLC Treated with PD-1 Blockade.
Cancer Discov
; 11(1): 59-67, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958579
18.
KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma.
Clin Cancer Res
; 27(9): 2604-2612, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33593884
19.
Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer.
Cell Rep
; 33(9): 108444, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33264619
20.
Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC.
Clin Cancer Res
; 26(12): 2849-2858, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046999