Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 41
Filtrar
Mais filtros

Intervalo de ano de publicação
1.
BMC Health Serv Res ; 24(1): 1225, 2024 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-39395982

RESUMO

Colombia is among the countries with the most robust financial protection against personal health spending in the world, with out-of-pocket spending ranking lowest across OECD countries. We investigate the evolution, distribution, and persistence of health spending by age group, sex, health care setting, health condition and geographic region for over 19 million users of Colombia's health system between 2013 and 2021 (contributory scheme). We use average patient-level expenditure data from the Health-Promoting Entities of the Ministry of Health and Social Protection. We applied multivariate statistical techniques such as multiple correspondence analysis, factor maps and correlations. For both sexes, average health expenditure increases gradually with age until 60 years, accelerating thereafter abruptly. Health conditions with the highest percentage of expenditure were those related to neoplasms, blood diseases, circulatory system, pregnancy, puerperium and perinatal period. We found that home-based care in Amazonía-Orinoquía is almost non-existent, and that outpatient care represents a high proportion in all age groups (over 65%) compared to the other regions. There is a strong persistence of expenditure from one year to the next (i.e. they can provide relevant information for prediction), especially in areas with a larger supply of health services such as Bogotá-Cundinamarca. To the authors' knowledge, this is the most comprehensive and detailed micro-analysis of health spending that has been developed for a Latin American country to date.


Assuntos
Gastos em Saúde , Colômbia , Humanos , Gastos em Saúde/estatística & dados numéricos , Feminino , Masculino , Pessoa de Meia-Idade , Adulto , Idoso , Adolescente , Pré-Escolar , Adulto Jovem , Lactente , Criança , Recém-Nascido
2.
Cost Eff Resour Alloc ; 21(1): 73, 2023 Oct 04.
Artigo em Inglês | MEDLINE | ID: mdl-37794468

RESUMO

BACKGROUND: Because of a change of government, the Colombian Ministry of Health and Social Protection is in the process of presenting a structural reform for the General System of Social Security in Health (GSSSH), in order to implement a 'preventive and predictive health model'. However, it will always be relevant to review and analyze the fiscal implications of any proposed public policy program, to protect financial sustainability and to promote the better functioning of the system in question. METHODS: To contribute to this topic, we have calculated, using a financial-actuarial approach, the loss ratio for the years 2017 to 2021 for the Capitation Payment Unit (CPU) for all the Health-Promoting Entities (HPE) for both contributory and subsidized schemes. This information, derived from public reports available on the official website of the National Health Superintendency, allows us to estimate the financial burden of the institutions that guarantee access to and provision of health services and technologies in Colombia. RESULTS: The study shows that close to half of the HPEs in Colombia (which represent 11.6 million affiliates) have CPU loss ratios of more than 100% for the year 2021, evidencing insufficient resources for the operation of health insurance. CONCLUSIONS: Finally, we propose some policy recommendations regarding the strengthening of informed decision-making to allow the healthy financial sustainability of the Colombian GSSSH.

3.
Clin Auton Res ; 29(2): 137-150, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30805869

RESUMO

PURPOSE: To review the epidemiology and pathophysiology of autonomic symptoms and signs during epileptic seizures. METHODS: We performed a systematic literature search on the following autonomic symptoms and signs during epileptic seizures: cardiovascular changes, respiratory manifestations, gastrointestinal symptoms, cutaneous manifestations, sexual and genital manifestations, and urinary symptoms. RESULTS: Autonomic symptoms and signs can represent the predominant symptom at the onset of a focal seizure, which would then lead to the seizure being classified as a focal onset autonomic seizure. Conversely, clinically relevant autonomic symptoms and signs frequently accompany seizures of focal, generalized, and/or unknown onset, but the seizure is regardless classified according to other, more relevant features. Autonomic symptoms and signs do not represent mere reactions to motor activity or other behavioral seizure manifestations, but rather they are generated by epileptic discharges affecting the central autonomic network. We have reviewed the localizing and lateralizing information currently available on the seizure onset zone and on seizure propagation pathways as provided by systematic analysis of specific autonomic seizure symptoms and signs. We present data on how autonomic seizure symptoms and signs are useful for gaining a better understanding of the anatomical and functional organization of the central autonomic network. Finally, we discuss the differential diagnosis of focal autonomic seizures with autonomic symptoms and signs representing the sole seizure manifestation versus various non-epileptic conditions. CONCLUSIONS: Autonomic seizure symptoms and signs are relevant in clinical epileptology and open a unique window on the functional organization and pathophysiology of the central autonomic network.


Assuntos
Sistema Nervoso Autônomo/fisiopatologia , Convulsões/fisiopatologia , Humanos
4.
Endoscopy ; 50(2): 119-127, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29065438

RESUMO

BACKGROUND AND STUDY AIM: The European guidelines for quality assurance in colorectal cancer screening and diagnosis contain postpolypectomy surveillance recommendations. They recommend follow-up intervals depending on the findings at index colonoscopy, and divide patients into a low-, intermediate- or high-risk group. The aim of this study was to assess the adherence of Austrian endoscopists to the European guidelines and to determine whether sending a reminder letter resulted in better adherence. METHODS: A single reminder letter containing the guidelines was sent to all endoscopists who participated in the Certificate of Quality for Screening Colonoscopy program in Austria. Adherence was assessed before and after the letter had been sent. Factors associated with adherence were investigated. RESULTS: We found poor baseline adherence to the guidelines. After the reminder letter, the adherence slightly improved in the low-risk group, but did not change in the intermediate-risk or high-risk groups. An adenoma detection rate of at least 20 % was associated with higher adherence rates. Generally, internists and hospitals showed better adherence compared with surgeons and private practices, respectively, both before and after the reminder letter. CONCLUSION: A single reminder letter was not enough to improve the poor adherence to the European postpolypectomy surveillance guidelines. Thus, future studies are required to identify and eliminate all factors responsible for nonadherence to postpolypectomy guidelines in order to reach the goal of a safe, effective, and cost-effective colorectal cancer prevention tool in the near future.


Assuntos
Colonoscopia/normas , Neoplasias Colorretais/diagnóstico , Detecção Precoce de Câncer/normas , Fidelidade a Diretrizes , Programas de Rastreamento/métodos , Idoso , Áustria/epidemiologia , Neoplasias Colorretais/epidemiologia , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Fatores de Tempo
5.
Br J Cancer ; 115(11): 1421-1429, 2016 Nov 22.
Artigo em Inglês | MEDLINE | ID: mdl-27764840

RESUMO

BACKGROUND: Prevalence of (pre)cancerous colorectal lesions are higher in men than in women, although transition rates from advanced lesions to cancer is similar in both sexes. Our aim was to investigate whether the sex-specific difference in incidence of premalignant colorectal lesions might be explained by the impact of risk factors. METHODS: A cross-sectional study analysing health check-up examinations and screening colonoscopies performed within a national quality assurance program. RESULTS: A total of 25 409 patients were included in this study, 50.8% were women. Median age for both sexes was 60 years (interquartile range (IQR) 54-67). A multivariable model showed that risk factors mediated only 0.6 of the 10.4% gender gap in adenoma and 0.47 of the 3.2% gender gap in advanced adenoma detection rate. Smoking was the only independent risk factor with a varying sex-specific effect (men OR 1.46, CI 1.29, 1.64, women OR 1.76, CI 1.53, 2.06) and advanced adenomas (men OR 1.06, CI 0.80-1.42; women OR 2.08, CI 1.52-2.83). Independent risk factors for adenomas were BMI (OR 1.35 per IQR, CI 1.25-1.47) and triglyceride level (OR 1.03 per IQR, CI 1.00-1.06); for advanced adenomas physical activity (none vs regular: OR 1.54, CI 1.18-2.00, occasional vs regular: OR 1.17, CI 1.00-1.38), cholesterol level (OR 1.13 per IQR, CI 1.02-1.25), blood glucose level (OR 1.05 per IQR, CI 1.01-1.09) and alcohol score (OR 1.09 per IQR, CI 1.01-1.18). CONCLUSIONS: Risk factors cannot explain higher prevalence rates in men. Results of this study strongly underline the need for sex-specific screening recommendations.


Assuntos
Neoplasias Colorretais/epidemiologia , Lesões Pré-Cancerosas/epidemiologia , Fatores Sexuais , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de Risco
6.
Endoscopy ; 48(12): 1102-1109, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27576182

RESUMO

Background and study aim: Screening colonoscopy only effectively prevents colorectal cancer if performed with high quality. The aim of this study was to analyze the detection rates of premalignant colorectal lesions in screening colonoscopies performed within a nationwide quality control program for screening colonoscopy in Austria. Methods: Data from electronic records of the screening program from its implementation in 2007 until December 2014 were analyzed in order to calculate detection rates for adenomas, advanced adenomas, polyps, and proximal lesions, and rates of cecal intubation, sedation, complications, and adequate bowel preparation. Results were evaluated to identify trends and changes in quality parameters over the 8-year study period. Results: During the study period, 301 endoscopists provided data from 159 246 screening colonoscopies. Mean age of screened individuals was 61.1 years, and 49.1 % were women. Significant increases over time were found for age- and sex-adjusted adenoma detection rates (ADRs), which increased from a mean of 22.2 % (SD 10.7 %) in 2007/2008 to 24.2 % (SD 11.6 %) in 2013/2014. On average, each endoscopist increased their individual ADR by + 1.5 percentage points per 2-year period (95 % confidence interval [CI] 0.9 - 2.2 percentage points; P < 0.01). Similarly, detection rates for proximal lesions rose from 15.8 % (SD 9.8 %) to 21.7 % (SD 13.3 %  + 2.5 percentage points per 2-year period, 95 %CI 1.9 - 3.1 percentage points; P < 0.01). ADR in men increased from 27.6 % in 2007/2008 (SD 11.1 %) to 29.2 % in 2013/2014 (SD 12.7 %; P < 0.01); ADR in women increased from 14.2 % (SD 7.1 %) in 2007/2008 to 19.0 % (SD 10.5 %) in 2013/2014 (P < 0.01). Advanced adenoma detection rates decreased during the study period, from 11.4 % (SD 9.0 %) in 2007/2008 to 7.6 % (SD 5.4 %) in 2013/2014 (P = 0.06) in men, and from 5.5 % (SD 5.3 %) in 2007/2008 to 4.0 % (SD 4.1 %) in 2013/2014 in women (P = 0.21). Conclusions: This study showed an improvement in the quality of screening colonoscopies performed within a quality assurance program in Austria between 2007 and 2014. Although, overall ADR increased significantly during the study period, there was a decrease in the rate of advanced adenoma detection.


Assuntos
Adenoma/diagnóstico por imagem , Colonoscopia/tendências , Neoplasias Colorretais/diagnóstico por imagem , Detecção Precoce de Câncer/tendências , Qualidade da Assistência à Saúde/tendências , Adenoma/patologia , Instituições de Assistência Ambulatorial/normas , Instituições de Assistência Ambulatorial/tendências , Áustria , Ceco , Colonoscópios/microbiologia , Colonoscopia/efeitos adversos , Colonoscopia/normas , Neoplasias Colorretais/patologia , Sedação Profunda , Detecção Precoce de Câncer/normas , Contaminação de Equipamentos , Feminino , Hospitais/normas , Hospitais/tendências , Humanos , Intubação Gastrointestinal , Masculino , Pessoa de Meia-Idade , Prática Privada/normas , Prática Privada/tendências , Garantia da Qualidade dos Cuidados de Saúde
7.
Clin Gastroenterol Hepatol ; 13(5): 956-62, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25151257

RESUMO

BACKGROUND & AIMS: Various types of liver disease are associated with an increased prevalence of colorectal adenomas. We investigated whether cirrhosis is a risk factor for colorectal neoplasia by analyzing colonoscopy findings from 2 cohorts of patients awaiting liver transplantation. METHODS: We performed a retrospective analysis to compare findings from colorectal cancer screenings of 567 adult patients with cirrhosis placed on the waitlist for liver transplantation with those from controls (matched for age, sex, body mass index, smoking, and diabetes). Rates of adenoma and advanced adenoma detection were adjusted owing to differences in rates of polypectomies performed in the 2 cohorts. RESULTS: Adenomas were detected in a significantly higher percentage of patients with cirrhosis (29.3%) than in controls (21.5%) (P = .0057; relative risk [RR], 1.36; 95% confidence interval [CI], 1.09-1.69); and patients with cirrhosis had a higher rate of advanced adenoma detection than controls (13.9% vs 7.7%; P = .0015; relative risk, 1.82; 95% CI, 1.25-2.64). A greater percentage of patients with alcoholic cirrhosis had neoplasias (34.3%) than controls (25.3%; P = .0350; RR, 1.36), and rates of advanced adenoma detection were 16.7% vs 10.2% (P = .0409; RR, 1.63). Adenomas were detected in 27.8% of patients with viral cirrhosis vs 15.9% of controls (P = .0061; RR, 1.74), with rates of advanced adenoma detection of 13.6% vs 5.0% (P = .0041; RR, 2.73). Similar proportions of patients with cirrhosis of other etiologies and controls were found to have colorectal neoplasias. CONCLUSIONS: Based on a retrospective analysis of colonoscopy findings from patients awaiting liver transplantation, those with alcoholic or viral cirrhosis are at higher risk of developing colorectal neoplasia and should be considered for earlier colonoscopy examination.


Assuntos
Adenoma/epidemiologia , Neoplasias Colorretais/epidemiologia , Cirrose Hepática/complicações , Estudos de Coortes , Colonoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos
8.
Endoscopy ; 47(3): 207-16, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25412094

RESUMO

BACKGROUND AND STUDY AIM: International studies have shown differences in the outcome of screening colonoscopies related to the endoscopist's specialty and setting of colonoscopy. The aim of this study was to investigate the impact of these two factors on quality parameters for screening colonoscopy in a quality-assured screening program. METHODS: Adenoma detection rate (ADR), cecal intubation rate (CIR), polypectomy rate, flat polyp detection rate, carcinoma detection rate, sedation rate, complication rates, and other parameters of 59 901 screening colonoscopies performed by 178 endoscopists were analyzed in relation to specialty (35 gastroenterologists: 10 066 colonoscopies [16.8 %]; 84 nongastroenterologists: 26 271 colonoscopies [43.9 %]; 59 surgeons: 23 564 [39.3 %]), and setting (hospital: 12 580 [21.6 %] colonoscopies; office: 45 781 [78.4 %] colonoscopies). RESULTS: The overall ADR was 20.5 % and the CIR was 95.6 %. The ADR did not show any statistical significance, either in relation to specialty or to setting. A significant difference in the CIR was found between hospital-based and office-based internists (98.5 % vs. 96.8 %, respectively; P  = 0.0005; odds ratio [OR] 2.2, 95 % confidence interval [CI] 1.4 - 3.4). Hospital-based internists had a significantly higher flat polyp detection rate (7.5 % vs. 4.1 %; P  = 0.02; OR 1.9, 95 %CI 1.1 - 3.2) and a significantly lower carcinoma detection rate (0.4 % vs. 0.6 %; P  = 0.03; OR 0.7, 95 %CI 0.5 - 1.0) compared with office-based internists. Complication rates were significantly lower among surgeons than among internists (0.1 % vs. 0.2 %; P  = 0.03; OR 0.5, 95 %CI 0.3 - 1.0). CONCLUSION: Endoscopists participating in the Austrian quality assurance program offered high quality screening colonoscopy regardless of their specialty and setting. The implementation of a standardized quality program is therefore a decisive factor in quality improvement of screening colonoscopy.


Assuntos
Adenoma/diagnóstico , Carcinoma/diagnóstico , Colonoscopia/normas , Neoplasias Colorretais/diagnóstico , Gastroenterologia/normas , Cirurgia Geral/normas , Adenoma/cirurgia , Idoso , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Áustria , Ceco , Pólipos do Colo/diagnóstico , Pólipos do Colo/cirurgia , Colonoscopia/efeitos adversos , Colonoscopia/estatística & dados numéricos , Neoplasias Colorretais/cirurgia , Detecção Precoce de Câncer/normas , Detecção Precoce de Câncer/estatística & dados numéricos , Feminino , Gastroenterologia/estatística & dados numéricos , Cirurgia Geral/estatística & dados numéricos , Hospitais/estatística & dados numéricos , Humanos , Hipnóticos e Sedativos/administração & dosagem , Medicina Interna/normas , Medicina Interna/estatística & dados numéricos , Intubação Gastrointestinal/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Garantia da Qualidade dos Cuidados de Saúde
9.
Endoscopy ; 47(10): 898-902, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26115462

RESUMO

BACKGROUND AND STUDY AIMS: European guidelines for quality assurance in colorectal cancer screening recommend snare resection for polyps > 5 mm. The aim of this study was to investigate polypectomy technique according to lesion size and shape, and to assess adherence of endoscopists enrolled in the national quality assurance program to the European guidelines. PATIENTS AND METHODS: This cohort study included screening colonoscopies performed between 2007 and 2013 within a quality assurance program in Austria. Resection technique was analyzed according to lesion characteristics and endoscopy facility (private practices, hospitals, outpatient clinics) before publication of the EU guidelines (2007 - 2010) and adherence to the guidelines after publication (2011 - 2013). All surveillance colonoscopies and examinations with missing data were excluded. RESULTS: A total of 128 969 screening colonoscopies performed by 278 endoscopy units were included. The polyp detection rate was 39.6 % (n = 47 797) and 95.6 % of polyps were resected. Of polyps ≥ 5 mm, 46.0 % were resected using forceps and were therefore not treated in accordance with the guidelines. Forceps polypectomy of lesions 5 - 10 mm and > 10 mm decreased significantly in hospitals after implementation of the guidelines (both P < 0.0001). In private practices, there was no difference in forceps usage for polyps of 5 - 10 mm (P = 0.41) before and after the guidelines, and for polyps > 10 mm forceps usage even increased (P < 0.0001). Endoscopists' forceps removal rates for polyps ≥ 5 mm correlated significantly with respective adenoma detection rates (P = 0.0007, r p  - 0.187) and cecal intubation rates (P = 0.0001, r p  - 0.303). Among endoscopists in private practices, internists had slightly lower forceps removal rates for polyps ≥ 5 mm than surgeons, both before (47.2 % vs. 50.7 %; P = 0.014) and after publication of the guidelines (51.9 % vs. 53.5 %; P = 0.161). CONCLUSIONS: This study confirmed the importance of the European guidelines. The inclusion of adequate resection technique as a quality indicator in colorectal cancer screening programs is recommended.


Assuntos
Competência Clínica , Colonoscópios/normas , Colonoscopia/normas , Neoplasias Colorretais/cirurgia , Detecção Precoce de Câncer/normas , Fidelidade a Diretrizes , Garantia da Qualidade dos Cuidados de Saúde , Áustria/epidemiologia , Colonoscopia/instrumentação , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/epidemiologia , Detecção Precoce de Câncer/métodos , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Morbidade/tendências , Estudos Retrospectivos , Instrumentos Cirúrgicos
10.
Surg Endosc ; 29(2): 466-73, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25005016

RESUMO

BACKGROUND: An endoscopists adenoma detection rate (ADR) of less than 20 % correlates with high risk for occurrence of interval cancer. The impact of high-definition (HD) imaging on the ADR is discussed controversially. We aimed to investigate whether detection rates of individual endoscopists increase within 1 year before and 1 year after the switch from standard to HD endoscopy. METHODS: This cohort study analyzed 6,330 screening colonoscopies (2,968 with standard and 3,362 with HD) performed by 42 endoscopists between November 2007 and March 2013 within a nationwide quality assurance program for screening colonoscopy. RESULTS: The ADR of endoscopists with a low ADR (<20 %) increased significantly higher (from 11.8 to 18.1 %, p = 0.003) than of those with a high ADR (≥ 20 %) (from 28.6 to 30.7 %, p = 0.439) after switch from standard to HD colonoscopes (p = 0.0076). The proportion of endoscopists with an ADR < 20 % decreased from 45 to 42.9 % (p = 0.593). There was no significant increase in age- and sex-adjusted detection rates of adenomas (20.2 vs 23.7 %; p = 0.089), advanced adenomas (4.7 vs 5.5 %; p = 0.479), flat adenomas (2.7 vs 3.1 %; p = 0.515), polyps (38.8 vs 41.5 %; p = 0.305), proximal polyps (18.5 vs 20 %; p = 0.469) and hyperplastic polyps (15 vs 17.2 %; p = 0.243) of endoscopists after switch to HD colonoscopes. There was no difference in detection rates of flat polyps (5.5 vs 5.5 %; p = 0.987). CONCLUSIONS: The use of HD scopes is associated with marginal improvement in adenoma detection rates limited to those endoscopists with low adenoma detection rates prior to its introduction.


Assuntos
Adenoma/diagnóstico , Competência Clínica/estatística & dados numéricos , Colonoscopia/métodos , Neoplasias Colorretais/diagnóstico , Erros de Diagnóstico/estatística & dados numéricos , Gastroenterologia , Processamento de Imagem Assistida por Computador/métodos , Idoso , Feminino , Seguimentos , Gastroenterologia/educação , Humanos , Masculino , Programas de Rastreamento/estatística & dados numéricos , Pessoa de Meia-Idade , Garantia da Qualidade dos Cuidados de Saúde , Reprodutibilidade dos Testes , Estudos Retrospectivos , Recursos Humanos
11.
Skinmed ; 13(4): 287-95; quiz 296, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26861426

RESUMO

Actinic prurigo is an idiopathic photodermatosis that affects the skin, as well as the labial and conjunctival mucosa in indigenous and mestizo populations of Latin America. It starts predominantly in childhood, has a chronic course, and is exacerbated with solar exposure. Little is known of its pathophysiology, including the known mechanisms of the participation of HLA-DR4 and an abnormal immunologic response with increase of T CD4+ lymphocytes. The presence of IgE, eosinophils, and mast cells suggests that it is a hypersensitivity reaction (likely type IVa or b). The diagnosis is clinical, and the presence of lymphoid follicles in the mucosal histopathologic study of mucosa is pathognomonic. The best available treatment to date is thalidomide, despite its secondary effects.


Assuntos
Fármacos Dermatológicos/uso terapêutico , Transtornos de Fotossensibilidade/fisiopatologia , Dermatopatias Genéticas/fisiopatologia , Talidomida/uso terapêutico , Antígeno HLA-DR4/genética , Humanos , Transtornos de Fotossensibilidade/diagnóstico , Transtornos de Fotossensibilidade/tratamento farmacológico , Dermatopatias Genéticas/diagnóstico , Dermatopatias Genéticas/tratamento farmacológico , Luz Solar/efeitos adversos , Talidomida/efeitos adversos
12.
Rev Chil Pediatr ; 86(5): 337-44, 2015.
Artigo em Espanhol | MEDLINE | ID: mdl-26342394

RESUMO

INTRODUCTION: Sepsis is a major cause of neonatal morbidity and mortality. OBJECTIVES: To detect the time when the bacterial growth curve is evidenced in the blood sample inoculated blood cultures and comparing the times of bacterial growth between Gram negative and Gram positive bacteria, among the types of neonatal sepsis and identifying microorganisms more often isolated from preterm and term. PATIENTS AND METHOD: A descriptive study. 114 positive blood cultures from 1,932 blood cultures taken from 01-May-2010 and 31-May-2014 were evaluated. Data were analyzed with Stata(®) 11.0. RESULTS: 5.9% of blood cultures had bacterial growth. The median and interquartile range of Gram negative times of bacterial growth was 11h (10-13h), for Gram positive coagulase-negative Staphylococcus different (CoNS) 12h (12-18h) and CoNS 42h (36-44h). 95.8% of Gram positive and 96% of Gram negative, were the times of bacterial growth≤24h incubation, whereas the 100% CoNS was positive≤62h of incubation. CONCLUSION: 100% of sepsis by Gram negative and Gram positive no CoNS and 90% of those caused by CoNS are identified in blood cultures in 48h, so we can conclude that to rule out sepsis, an incubation period of 48h in blood cultures is sufficient.


Assuntos
Bacteriemia/diagnóstico , Bactérias Gram-Negativas/isolamento & purificação , Bactérias Gram-Positivas/isolamento & purificação , Sepse/diagnóstico , Bacteriemia/microbiologia , Hemocultura , Feminino , Infecções por Bactérias Gram-Negativas/diagnóstico , Infecções por Bactérias Gram-Negativas/microbiologia , Infecções por Bactérias Gram-Positivas/diagnóstico , Infecções por Bactérias Gram-Positivas/microbiologia , Humanos , Recém-Nascido , Masculino , Sepse/microbiologia , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/microbiologia , Staphylococcus/enzimologia , Staphylococcus/isolamento & purificação , Fatores de Tempo
13.
Ginecol Obstet Mex ; 82(1): 64-9, 2014 Jan.
Artigo em Espanhol | MEDLINE | ID: mdl-24701862

RESUMO

Pemphigus vulgaris is a bullous, autoimmune, mucocutaneous and potentially fatal disease. Association between pemphigus vulgaris and pregnancy is little frequent. Evolution of this autoimmune disease is different, because of the hormone and immunological disorders related to pregnancy. Adverse effects on fetus should be taken into account, by drugs administered to the mother and by the transference of antibodies by transplacentary route. This paper reports the case of a 21-year-old female patient with diagnosis of pemphigus vulgaris since 14 years old, who assisted to consultation due to a pregnancy of three-months and exacerbation of the disease.


Assuntos
Pênfigo/patologia , Complicações na Gravidez/patologia , Anticorpos/imunologia , Feminino , Humanos , Pênfigo/complicações , Pênfigo/imunologia , Gravidez , Complicações na Gravidez/imunologia , Adulto Jovem
14.
Ginecol Obstet Mex ; 82(1): 1-8, 2014 Jan.
Artigo em Espanhol | MEDLINE | ID: mdl-24701855

RESUMO

BACKGROUND: During reproductive age 75% of women experience at least one episode of vulvovaginal candidiasis, approximately 6% to 55% of healthy women are asymptomatic carriers. In Mexico there are no current data of the frequency of vaginal colonization by Candida in the general population. OBJECTIVE: To determine the frequency of the colonization by Candida species in asymptomatic women. MATERIAL AND METHODS: A descriptive, open, observational, prospective, cross sectional study was carried out in adult women attending the cervical cytology department at Hospital General Dr. Manuel Gea González in Mexico City. The study was conducted from January to May 2013. RESULTS: There were a total of 150 samples of asymptomatic women between 15 and 77 years (mean 43 years). We obtained positive culture for Candida in 19 samples (12.6 %). 47% of the species corresponded to C. albicans, however, it was isolated other species such as C. krusei in 26%, C. glabrata (21%) and C. tropicalis by 15%. CONCLUSIONS: Our findings are consistent with data reported in the literature. It is relevant the isolation of non-albicans Candida species. These findings may be caused by an increase of inappropriate therapies.


Assuntos
Candida albicans/isolamento & purificação , Candida/isolamento & purificação , Candidíase Vulvovaginal/epidemiologia , Adolescente , Adulto , Idoso , Candidíase Vulvovaginal/microbiologia , Estudos Transversais , Feminino , Humanos , México/epidemiologia , Pessoa de Meia-Idade , Estudos Prospectivos , Adulto Jovem
15.
Gac Med Mex ; 150(1): 101-5, 2014.
Artigo em Espanhol | MEDLINE | ID: mdl-24481437

RESUMO

Patients with a first primary melanoma are known to have an increased risk of being diagnosed with another primary melanoma. We present the case of a 42-year-old male patient with multiple primary melanoma who was admitted to the dermatology department at the general hospital "Dr Manuel Gea González" in Mexico City. Incidence, risk factors and prognosis are discussed in this review.


Assuntos
Neoplasias Primárias Múltiplas , Neoplasias Cutâneas , Adulto , Humanos , Masculino , Melanoma , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Cutâneas/diagnóstico
16.
Curr Probl Diagn Radiol ; 53(5): 567-569, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38714393

RESUMO

Medical imaging is essential for the proper diagnosis and treatment of many diseases. The literature has found that medical imaging generally accounts for a significant percentage of total healthcare spending. We analyzed a national database between 2013 and 2021, with more than 19 million patients on average, to review which health conditions account for the highest spending on medical imaging in the Colombian health system. We segmented the analysis by type of medical imaging, life cycles, health condition and sex. Our findings indicate that cardiac and mental illnesses account for the highest per capita spending on medical imaging, especially for the elderly. As a proportion of total expenditure, hypertension and tuberculosis are added, with special emphasis on the infancy-childhood life cycle.


Assuntos
Diagnóstico por Imagem , Gastos em Saúde , Humanos , Colômbia , Diagnóstico por Imagem/economia , Gastos em Saúde/estatística & dados numéricos , Feminino , Masculino , Adulto , Criança , Pessoa de Meia-Idade , Lactente , Pré-Escolar , Adolescente , Idoso
17.
Front Neurol ; 15: 1384206, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38737346

RESUMO

Introduction: Nosocomial infectious ventriculitis caused by multidrug-resistant (MDR) Gram-negative bacilli associated with external ventricular drainage (EVD) placement poses a significant mortality burden and hospital costs. Objectives: This study aims to analyze the characteristics, ventriculitis evolution, treatment, and outcomes of patients with ventriculitis due to MDR Gram-negative bacilli associated with EVD placement. Methods: A retrospective cohort study focusing on patients with nosocomial infection caused by MDR Gram-negative bacilli while on EVD was conducted from 2019 to 2022. Medical, laboratory, and microbiological records were collected. The antibiotic resistance of the Gram-negative bacilli isolated in the cerebrospinal fluid (CSF) of patients was analyzed. The risk factors were identified using univariate risk models and were analyzed using survival curves (Cox regression). An adjusted Cox proportional hazards model was also constructed. Results: Among 530 patients with suspected EVD-associated ventriculitis, 64 patients with isolation of Gram-negative bacilli in CSF were included. The estimated mortality was 78.12%. Hemorrhages (intracranial, subarachnoid, and intraventricular) were observed in 69.8% of patients. Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most frequently isolated bacilli. In the univariate analysis, significant risk factors for mortality included arterial hypertension, a Glasgow Coma Scale (GCS) score of ≤ 8, invasive mechanical ventilation (IMV) upon hospital admission and during hospitalization, septic shock, and ineffective treatment. The adjusted Cox proportional hazards model revealed that septic shock (HR = 3.3, 95% CI = 1.5-7.2; p = 0.003) and ineffective treatment (HR = 3.2, 1.6-6.5, 0.001) were significant predictors. A high resistance to carbapenems was found for A. baumannii (91.3%) and P. aeruginosa (80.0%). Low resistance to colistin was found for A. baumannii (4.8%) and P. aeruginosa (12.5%). Conclusion: Ineffective treatment was an independent hazard factor for death in patients with ventriculitis caused by MDR Gram-negative bacilli associated with EVD.

19.
Heliyon ; 9(6): e16418, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37274712

RESUMO

This study aims to examine the factors involved in the technological acceptance of e-commerce among young university students. The research is focused on the articulation between the Technology Acceptance Model (TAM) and the Theory of Planned Behavior (TPB) by collecting secondary data and conducting a survey with 376 young university students, validated by using structural equations (SEM). The predominant factors and variables involved in the adoption of e-commerce by young university students in Medellín were identified. The results show that the attitude towards usage has a positive effect on usage intention because people consider a website to be useful and trust builds regarding usage intention, which will enable to make the transaction in an easier and safer way. In conclusion, perceived usefulness comes before attitude towards usage, and thus the main direct antecedent of the intention to use e-commerce is established.

20.
Behav Sci (Basel) ; 13(5)2023 May 05.
Artigo em Inglês | MEDLINE | ID: mdl-37232619

RESUMO

University dropout is a problem that has raised great concern in institutions of higher education. For this reason, academic institutions need to study the phenomenon and come up with alternatives that contribute to the improvement of students' individual commitments. The aim is to examine the dimensions influencing the decision of university students to drop out. A quantitative approach study was carried out, based on a cross-sectional exploratory-descriptive field design, in which 372 students participated. According to the participants, one of the dimensions that influence the decision to leave the university is the support of the institutions to the continuity of the motivation processes to the student body, since the easy access to the credits is greater than the scholarships granted, which coincides with the financing restrictions of university students in developing countries. In conclusion, it is observed that the communication between managers, teachers, and students is a key factor in the processes of academic retention as a strategy to combat the phenomenon of university desertion.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA