Detalhe da pesquisa
1.
Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation.
Metabolomics
; 16(4): 50, 2020 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32285223
2.
International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis.
Anal Chem
; 91(22): 14407-14416, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31638379
3.
Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma.
Anal Chem
; 89(1): 656-665, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27959516
4.
A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma.
Invest New Drugs
; 30(1): 341-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20683637
5.
Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications.
Cells
; 11(20)2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36291153
6.
Presence of human breast cancer xenograft changes the diurnal profile of amino acids in mice.
Sci Rep
; 12(1): 1008, 2022 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35046467
7.
De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy.
Autophagy
; 16(6): 1044-1060, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31517566
8.
An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
Cancer Chemother Pharmacol
; 62(5): 769-78, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18193424
9.
Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
Cancer Chemother Pharmacol
; 82(5): 911-912, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30173339
10.
Modulation of Plasma Metabolite Biomarkers of the MAPK Pathway with MEK Inhibitor RO4987655: Pharmacodynamic and Predictive Potential in Metastatic Melanoma.
Mol Cancer Ther
; 16(10): 2315-2323, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28637716
11.
Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies.
J Clin Oncol
; 23(18): 4152-61, 2005 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15961763
12.
A validated liquid chromatographic-tandem mass spectroscopy method for the quantification of abiraterone acetate and abiraterone in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci
; 843(2): 262-7, 2006 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-16809076
13.
Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation.
Mol Cancer Ther
; 15(6): 1412-24, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048952
14.
Inter-Laboratory Robustness of Next-Generation Bile Acid Study in Mice and Humans: International Ring Trial Involving 12 Laboratories.
J Appl Lab Med
; 1(2): 129-142, 2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33626781
15.
Validation of liquid chromatography assay for the quantitation of (Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]propionic acid (SU006668) in human plasma and its application to a phase I clinical trial.
J Chromatogr B Analyt Technol Biomed Life Sci
; 785(1): 175-86, 2003 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12535850
16.
Development and validation of a liquid chromatography/tandem mass spectrometry method for the determination of the novel anticancer agent 17-DMAG in human plasma.
Rapid Commun Mass Spectrom
; 20(19): 2845-50, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16941534