Detalhe da pesquisa
1.
Design, synthesis, molecular modelling and biological evaluation of novel 6-amino-5-cyano-2-thiopyrimidine derivatives as potent anticancer agents against leukemia and apoptotic inducers.
J Enzyme Inhib Med Chem
; 39(1): 2304625, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348824
2.
Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells.
J Enzyme Inhib Med Chem
; 38(1): 405-422, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458403
3.
Synthesis of Dihydropyrimidines: Isosteres of Nifedipine and Evaluation of Their Calcium Channel Blocking Efficiency.
Molecules
; 28(2)2023 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677842
4.
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Pyrimidine Derivatives as Potential Calcium Channel Blockers.
Molecules
; 28(12)2023 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37375424
5.
Novel 2-Thiouracil-5-Sulfonamide Derivatives: Design, Synthesis, Molecular Docking, and Biological Evaluation as Antioxidants with 15-LOX Inhibition.
Molecules
; 28(4)2023 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36838913
6.
Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19.
Bioorg Chem
; 128: 106092, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985159
7.
Synthesis of Novel 2-Thiouracil-5-Sulfonamide Derivatives as Potent Inducers of Cell Cycle Arrest and CDK2A Inhibition Supported by Molecular Docking.
Int J Mol Sci
; 22(21)2021 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769385
8.
Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity.
Bioorg Chem
; 104: 104249, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911199
9.
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents.
Molecules
; 23(11)2018 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30413058
10.
Synthesis and Evaluation of Cytotoxic Activity of Certain Benzo[h]chromene Derivatives.
Anticancer Agents Med Chem
; 21(8): 963-986, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32981512
11.
Synthesis of certain pyrimidine derivatives as antimicrobial agents and anti-inflammatory agents.
Molecules
; 15(3): 1882-90, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20336018
12.
Synthesis and in vitro antitumor activity of new substituted thiopyrimidine acyclic nucleosides and their thioglycoside analogs.
Nucleosides Nucleotides Nucleic Acids
; 28(4): 261-74, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20183580