Detalhe da pesquisa
1.
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.
Mol Cell
; 82(13): 2458-2471.e9, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35550257
2.
Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Genes Dev
; 34(17-18): 1161-1176, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820036
3.
Proteogenomic profiling uncovers differential therapeutic vulnerabilities between TCF3::PBX1 and TCF3::HLF translocated B-cell acute lymphoblastic leukemia.
Haematologica
; 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38426288
4.
Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification.
Acta Neuropathol
; 145(5): 651-666, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014508
5.
Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.
J Neurooncol
; 163(1): 143-158, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37183219
6.
ClustMMRA v2: A Scalable Computational Pipeline for the Identification of MicroRNA Clusters Acting Cooperatively on Tumor Molecular Subgroups.
Adv Exp Med Biol
; 1385: 259-279, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352218
7.
PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence.
Proc Natl Acad Sci U S A
; 112(46): 14278-83, 2015 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578773
8.
Immunohistochemistry as a tool to identify ELP1-associated medulloblastoma.
Acta Neuropathol
; 143(4): 523-525, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199222
9.
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.
Mol Cell
; 33(4): 483-95, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19250909
10.
Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma.
Acta Neuropathol
; 141(6): 975-978, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33866410
11.
MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.
FASEB J
; 29(5): 1817-29, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25636740
12.
Introduction. Pediatric brain tumor.
Neurosurg Focus
; 48(1): E1, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896080
13.
SHH medulloblastoma in a young adult with a TCF4 germline pathogenic variation.
Acta Neuropathol
; 137(4): 675-678, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30848346
14.
SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Cell Death Differ
; 31(2): 170-187, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38062245
15.
Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression.
Dev Cell
; 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38834071
16.
Developmental basis of SHH medulloblastoma heterogeneity.
Nat Commun
; 15(1): 270, 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191555
17.
Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression.
J Neurosci
; 32(19): 6600-10, 2012 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22573682
18.
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins.
J Biol Chem
; 287(13): 10509-10524, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22315224
19.
Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models.
Front Oncol
; 13: 1166063, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377921
20.
Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups.
Nat Commun
; 14(1): 6669, 2023 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863903