Detalhe da pesquisa
1.
Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome.
Hum Brain Mapp
; 45(1): e26553, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38224541
2.
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs.
Hum Brain Mapp
; 43(1): 300-328, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33615640
3.
Understanding Exposure-Receptor Occupancy Relationships for Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators across a Range of Preclinical and Clinical Studies.
J Pharmacol Exp Ther
; 377(1): 157-168, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33541889
4.
Spatial Covariance of Cholinergic Muscarinic M1 /M4 Receptors in Parkinson's Disease.
Mov Disord
; 36(8): 1879-1888, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33973693
5.
Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study.
Mol Psychiatry
; 25(11): 2818-2831, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31358905
6.
Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size.
Mol Psychiatry
; 25(8): 1822-1834, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29895892
7.
A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia.
Front Cell Neurosci
; 17: 1124333, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36909280
8.
Targeting the Type 5 Metabotropic Glutamate Receptor: A Potential Therapeutic Strategy for Neurodegenerative Diseases?
Front Pharmacol
; 13: 893422, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35645791
9.
A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M1 receptor agonist HTL0018318 in patients with mild-to-moderate Alzheimer's disease.
Alzheimers Dement (N Y)
; 8(1): e12273, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35229025
10.
Lessons learned from using fMRI in the early clinical development of a mu-opioid receptor antagonist for disorders of compulsive consumption.
Psychopharmacology (Berl)
; 238(5): 1255-1263, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900526
11.
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.
JAMA Psychiatry
; 78(1): 47-63, 2021 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32857118
12.
Cholinergic muscarinic M1/M4 receptor networks in dementia with Lewy bodies.
Brain Commun
; 2(2): fcaa098, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32954342
13.
The muscarinic M1 receptor modulates associative learning and memory in psychotic disorders.
Neuroimage Clin
; 27: 102278, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32563036
14.
Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness.
Am J Psychiatry
; 177(7): 589-600, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32046535
15.
Cholinergic muscarinic M1 and M4 receptors as therapeutic targets for cognitive, behavioural, and psychological symptoms in psychiatric and neurological disorders.
Drug Discov Today
; 24(12): 2307-2314, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31499186
16.
Influence of muscarinic M1 receptor antagonism on brain choline levels and functional connectivity in medication-free subjects with psychosis: A placebo controlled, cross-over study.
Psychiatry Res Neuroimaging
; 290: 5-13, 2019 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31252222
17.
Relationship between muscarinic M1 receptor binding and cognition in medication-free subjects with psychosis.
Neuroimage Clin
; 18: 713-719, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29560312
18.
Dopamine in high-risk populations: A comparison of subjects with 22q11.2 deletion syndrome and subjects at ultra high-risk for psychosis.
Psychiatry Res Neuroimaging
; 272: 65-70, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29174435
19.
The effect of the muscarinic M1 receptor antagonist biperiden on cognition in medication free subjects with psychosis.
Eur Neuropsychopharmacol
; 27(9): 854-864, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28689687
20.
Cortical Morphology Differences in Subjects at Increased Vulnerability for Developing a Psychotic Disorder: A Comparison between Subjects with Ultra-High Risk and 22q11.2 Deletion Syndrome.
PLoS One
; 11(11): e0159928, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27828960