Detalhe da pesquisa
1.
Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens.
Infect Immun
; 90(5): e0005922, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416705
2.
Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors.
Bioorg Med Chem
; 26(8): 1727-1739, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555419
3.
Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs.
J Biol Chem
; 290(11): 6789-98, 2015 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605717
4.
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
J Biol Chem
; 288(13): 9428-37, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23396967
5.
Advances in luminescence-based technologies for drug discovery.
Expert Opin Drug Discov
; 18(1): 25-35, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36562206
6.
Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes.
Nat Commun
; 14(1): 4798, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558718
7.
A unique borrelial protein facilitates microbial immune evasion.
mBio
; 14(5): e0213523, 2023 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37830812
8.
Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development.
Science
; 379(6628): eabl3837, 2023 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36634189
9.
Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells.
J Cell Physiol
; 227(5): 1960-71, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21732367
10.
Application of biophysical methods for improved protein production and characterization: A case study on an high-temperature requirement A-family bacterial protease.
Protein Sci
; 31(12): e4498, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36334045
11.
Application of temperature-responsive HIS-tag fluorophores to differential scanning fluorimetry screening of small molecule libraries.
Front Pharmacol
; 13: 1040039, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36506591
12.
Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells.
Sci Rep
; 12(1): 17372, 2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36253497
13.
Allosteric binders of ACE2 are promising anti-SARS-CoV-2 agents.
bioRxiv
; 2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313579
14.
Allosteric Binders of ACE2 Are Promising Anti-SARS-CoV-2 Agents.
ACS Pharmacol Transl Sci
; 5(7): 468-478, 2022 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35821746
15.
Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.
ACS Chem Biol
; 17(9): 2471-2482, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36049119
16.
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.
J Med Chem
; 65(12): 8303-8331, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35696646
17.
Hybrid In Silico Approach Reveals Novel Inhibitors of Multiple SARS-CoV-2 Variants.
ACS Pharmacol Transl Sci
; 4(5): 1675-1688, 2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34608449
18.
Applications of Differential Scanning Fluorometry and Related Technologies in Characterization of Protein-Ligand Interactions.
Methods Mol Biol
; 2089: 47-68, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31773647
19.
An OpenData portal to share COVID-19 drug repurposing data in real time.
bioRxiv
; 2020 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511420
20.
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.
Sci Transl Med
; 12(530)2020 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051227