Detalhe da pesquisa
1.
Small Molecule Therapeutics in the Pipeline Targeting for Triple-Negative Breast Cancer: Origin, Challenges, Opportunities, and Mechanisms of Action.
Int J Mol Sci
; 25(11)2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38892472
2.
Iron-Imine Cocktail in Drug Development: A Contemporary Update.
Int J Mol Sci
; 25(4)2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396940
3.
Molecular Research in Pancreatic Cancer: Small Molecule Inhibitors, Their Mechanistic Pathways and Beyond.
Curr Issues Mol Biol
; 45(3): 1914-1949, 2023 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975494
4.
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors.
J Pineal Res
; 74(2): e12847, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36456538
5.
Small Molecule EGFR Inhibitors as Anti-Cancer Agents: Discovery, Mechanisms of Action, and Opportunities.
Int J Mol Sci
; 24(3)2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768973
6.
Ligand-based virtual screening, molecular docking, and molecular dynamics of eugenol analogs as potential acetylcholinesterase inhibitors with biological activity against Spodoptera frugiperda.
Mol Divers
; 26(4): 2025-2037, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529209
7.
Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies.
Int J Mol Sci
; 23(7)2022 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409064
8.
Ligand-Based Virtual Screening and Molecular Docking of Benzimidazoles as Potential Inhibitors of Triosephosphate Isomerase Identified New Trypanocidal Agents.
Int J Mol Sci
; 23(17)2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36077439
9.
Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice.
J Pineal Res
; 62(4)2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28247434
10.
Mechanisms of isoproterenol-induced cardiac mitochondrial damage: protective actions of melatonin.
J Pineal Res
; 58(3): 275-90, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25652673
11.
Alpha-lipoic acid and N-acetylcysteine protects intensive swimming exercise-mediated germ-cell depletion, pro-oxidant generation, and alteration of steroidogenesis in rat testis.
Mol Reprod Dev
; 81(9): 833-50, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25104294
12.
"Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: a mechanistic insight".
Food Chem Toxicol
; : 114813, 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38876380
13.
Comparative Analysis of a Secondary Metabolite Profile from Roots and Leaves of Iostephane heterophylla by UPLC-MS and GC-MS.
ACS Omega
; 9(5): 5429-5439, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343925
14.
Structure-based Virtual Screening from Natural Products as Inhibitors of SARS-CoV-2 Spike Protein and ACE2-h Receptor Binding and their Biological Evaluation In vitro.
Med Chem
; 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38204279
15.
Azithromycin in combination with riboflavin decreases the severity of Staphylococcus aureus infection induced septic arthritis by modulating the production of free radicals and endogenous cytokines.
Inflamm Res
; 62(3): 259-73, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23229721
16.
An integrated strategy to explore the potential role of melatonin against copper-induced adrenaline toxicity in rat cardiomyocytes: Insights into oxidative stress, inflammation, and apoptosis.
Int Immunopharmacol
; 120: 110301, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224648
17.
Melatonin protects against ketorolac induced gastric mucosal toxic injuries through molecular mechanism associated with the modulation of Arylakylamine N-Acetyltransferase (AANAT) activity.
Chem Biol Interact
; 382: 110611, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37348669
18.
Insights into the antioxidative mechanisms of melatonin in ameliorating chromium-induced oxidative stress-mediated hepatic and renal tissue injuries in male Wistar rats.
Food Chem Toxicol
; 173: 113630, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36708861
19.
Oleic acid prevents erythrocyte death by preserving haemoglobin and erythrocyte membrane proteins.
Free Radic Biol Med
; 202: 17-33, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36965537
20.
Fused Furan Moieties from Enol-like Compounds and ß-Keto Sulfoxonium Ylides Involving sp2 C-H Activation and Concomitant Tandem C-O Annulation.
Org Lett
; 25(24): 4493-4497, 2023 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37294033