Detalhe da pesquisa
1.
Chronic arsenic exposure induces malignant transformation of human HaCaT cells through both deterministic and stochastic changes in transcriptome expression.
Toxicol Appl Pharmacol
; 484: 116865, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38373578
2.
Clonal variability in chromosomal instability as a potential driver in the acquisition of tumorigenic phenotype in chronic arsenic-exposed and hsa-miR-186 overexpressing human keratinocytes.
Toxicol Appl Pharmacol
; 479: 116730, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37866707
3.
miR-186 induces tetraploidy in arsenic exposed human keratinocytes.
Ecotoxicol Environ Saf
; 256: 114823, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36989553
4.
miRNA dysregulation is an emerging modulator of genomic instability.
Semin Cancer Biol
; 76: 120-131, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33979676
5.
Zinc supplementation prevents mitotic accumulation in human keratinocyte cell lines upon environmentally relevant arsenic exposure.
Toxicol Appl Pharmacol
; 454: 116255, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36162444
6.
Chronic arsenic exposure suppresses ATM pathway activation in human keratinocytes.
Toxicol Appl Pharmacol
; 446: 116042, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35513056
7.
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Arch Toxicol
; 96(4): 987-1007, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122514
8.
Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer.
Arch Toxicol
; 95(7): 2351-2365, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34032870
9.
Arsenite Exposure Displaces Zinc from ZRANB2 Leading to Altered Splicing.
Chem Res Toxicol
; 33(6): 1403-1417, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32274925
10.
The novel p.Ser263Phe mutation in the human high-affinity choline transporter 1 (CHT1/SLC5A7) causes a lethal form of fetal akinesia syndrome.
Hum Mutat
; 40(10): 1676-1683, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31299140
11.
Multidrug Resistance Protein 1 (MRP1/ABCC1)-Mediated Cellular Protection and Transport of Methylated Arsenic Metabolites Differs between Human Cell Lines.
Drug Metab Dispos
; 46(8): 1096-1105, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29752257
12.
Cellular arsenic transport pathways in mammals.
J Environ Sci (China)
; 49: 38-58, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007179
13.
A novel pathway for arsenic elimination: human multidrug resistance protein 4 (MRP4/ABCC4) mediates cellular export of dimethylarsinic acid (DMAV) and the diglutathione conjugate of monomethylarsonous acid (MMAIII).
Mol Pharmacol
; 86(2): 168-79, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24870404
14.
Chronic arsenic exposure suppresses proteasomal and autophagic protein degradation.
Environ Toxicol Pharmacol
; 107: 104398, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38403142
15.
Obesogenic polystyrene microplastic exposures disrupt the gut-liver-adipose axis.
Toxicol Sci
; 198(2): 210-220, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38291899
16.
Altered splicing factor and alternative splicing events in a mouse model of diet- and polychlorinated biphenyl-induced liver disease.
Environ Toxicol Pharmacol
; 103: 104260, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37683712
17.
Zinc supplementation prevents arsenic-induced dysregulation of ZRANB2 splice function.
Environ Toxicol Pharmacol
; 94: 103921, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764259
18.
Delineating the Effects of Passaging and Exposure in a Longitudinal Study of Arsenic-Induced Squamous Cell Carcinoma in a HaCaT Cell Line Model.
Toxicol Sci
; 185(2): 184-196, 2022 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730829
19.
Temporal Modulation of Differential Alternative Splicing in HaCaT Human Keratinocyte Cell Line Chronically Exposed to Arsenic for up to 28 Wk.
Environ Health Perspect
; 130(1): 17011, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35072517
20.
Evaluation of the serum catalase and myeloperoxidase activities in chronic arsenic-exposed individuals and concomitant cytogenetic damage.
Toxicol Appl Pharmacol
; 249(1): 47-54, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20732340