Detalhe da pesquisa
1.
Secretome of Cancer-Associated Fibroblasts (CAFs) Influences Drug Sensitivity in Cancer Cells.
J Proteome Res
; 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38767394
2.
A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer.
Br J Cancer
; 129(1): 38-45, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120671
3.
Searching for treatments for non-G12C-KRAS mutant cancers.
Br J Cancer
; 125(5): 625-626, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33859342
4.
Intermittent schedules of the oral RAF-MEK inhibitor CH5126766/VS-6766 in patients with RAS/RAF-mutant solid tumours and multiple myeloma: a single-centre, open-label, phase 1 dose-escalation and basket dose-expansion study.
Lancet Oncol
; 21(11): 1478-1488, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33128873
5.
Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation.
Metabolomics
; 16(4): 50, 2020 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32285223
6.
Radiological evaluation of malignant pleural mesothelioma - defining distant metastatic disease.
BMC Cancer
; 20(1): 1210, 2020 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33298007
7.
Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study.
Lancet Oncol
; 20(8): 1124-1135, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31257177
8.
Target-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre.
Br J Cancer
; 119(8): 922-927, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30318518
9.
Safety, efficacy and survival of patients with primary malignant brain tumours (PMBT) in phase I (Ph1) trials: the 12-year Royal Marsden experience.
J Neurooncol
; 139(1): 107-116, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29637509
10.
SARS-CoV-2 vaccination and phase 1 cancer clinical trials.
Lancet Oncol
; 22(3): 298-301, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571468
11.
A study of motivations and expectations of patients seen in phase 1 oncology clinics.
Cancer
; 122(22): 3501-3508, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27716902
12.
Antibody-drug conjugates--an emerging class of cancer treatment.
Br J Cancer
; 114(4): 362-7, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26742008
13.
Insights into significance of combined inhibition of MEK and m-TOR signalling output in KRAS mutant non-small-cell lung cancer.
Br J Cancer
; 115(5): 549-52, 2016 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27441499
14.
Hyperglycemia and Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin (PI3K/AKT/mTOR) Inhibitors in Phase I Trials: Incidence, Predictive Factors, and Management.
Oncologist
; 21(7): 855-60, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27151652
15.
Characterisation of the Phosphatidylinositol 3-Kinase Pathway in Non-Small Cell Lung Cancer Cells Isolated from Pleural Effusions.
Oncology
; 90(5): 280-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27082424
16.
Correction to: Radiological evaluation of malignant pleural mesothelioma - defining distant metastatic disease.
BMC Cancer
; 21(1): 245, 2021 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33685408
17.
A risk-based approach to experimental early phase clinical trials during the COVID-19 pandemic.
Lancet Oncol
; 21(7): 889-891, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32615107
18.
Percentage Change in Plasma Cytokeratin 18 Is Associated with Clinical Outcomes in Patients Receiving Pemetrexed and Carboplatin for the Adenocarcinoma Subtype of NSCLC.
Oncology
; 89(1): 53-9, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25766505
19.
Phase I trials in patients with relapsed, advanced upper gastrointestinal carcinomas: experience in a specialist unit.
Gastric Cancer
; 17(4): 621-629, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24445485
20.
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation.
J Clin Invest
; 134(2)2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934611