Detalhe da pesquisa
1.
Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles.
Int J Mol Sci
; 23(21)2022 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361896
2.
New phenylaniline derivatives as modulators of amyloid protein precursor metabolism.
Bioorg Med Chem
; 26(8): 2151-2164, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29559198
3.
Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure.
Bioorg Med Chem
; 26(12): 3296-3307, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29753566
4.
Development and validation of a reversed-phase HPLC method for the quantification of paclitaxel in different PLGA nanocarriers.
Electrophoresis
; 38(19): 2536-2541, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28370074
5.
Design, synthesis and biological evaluation of potent FAAH inhibitors.
Bioorg Med Chem Lett
; 26(11): 2701-5, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27117424
6.
Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors.
Bioorg Med Chem
; 23(22): 7340-7, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526740
7.
Switching cannabinoid response from CB(2) agonists to FAAH inhibitors.
Bioorg Med Chem Lett
; 24(5): 1322-6, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24508127
8.
High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists.
Eur J Med Chem
; 241: 114620, 2022 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933788
9.
Benzo[d]thiazol-2(3H)-ones as new potent selective CB2 agonists with anti-inflammatory properties.
Eur J Med Chem
; 165: 347-362, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30583970
10.
Development of novel oxazolo[5,4-d]pyrimidines as competitive CB2 neutral antagonists based on scaffold hopping.
Eur J Med Chem
; 146: 68-78, 2018 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29360044
11.
Synthesis and biological evaluation of ferrocene-based cannabinoid receptor 2 ligands.
Future Med Chem
; 10(6): 631-638, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29419319
12.
Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands.
Eur J Med Chem
; 138: 964-978, 2017 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28756263
13.
Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents.
Eur J Med Chem
; 115: 393-405, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27031215
14.
Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.
J Med Chem
; 59(18): 8422-40, 2016 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27538123
15.
Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.
ACS Med Chem Lett
; 6(2): 198-203, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25699149
16.
Inhibition of tumor cell growth and angiogenesis by 7-aminoalkoxy-4-aryloxy-quinazoline ureas, a novel series of multi-tyrosine kinase inhibitors.
Eur J Med Chem
; 79: 369-81, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747748
17.
4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.
J Med Chem
; 55(20): 8948-52, 2012 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23017078