[Perforating granulomatous folliculitis in Becker's nevus (author's transl)]. / Folliculitis granulomatosa perforans in einem Becker-Naevus.

Acneform lesions strictly confined to a Becker's nevus were observed in a 18-year-old man. Histologically, a granulomatous folliculitis with partial destruction of the epithelial root sheath and follicular cysts with focal penetration of keratin into the surrounding dermis were present, ruling out acne vulgaris. The concept of Becker's nevus as a complex nevogenic process, affecting ectodermal, neuroectodermal, and mesenchymal structures, also in terms of dysfunction of the pilary complex, is suggested.

[8-Methoxypsoralen (8-MOP)-a new galenic form and its relation to 8-MOP serum levels (author's transl)]. / 8-Methoxypsoralen (8-MOP) in neuer galenischer Zubereitung und seine Beziehung zum 8-MOP-Serumspiegel.

A bioequivalence study was performed with two different 8-MOP preparations. Thirty-eight patients participated in the investigation. We compared a product already marketed containing a micronized powder in hard gelatine capsules with a new product in soft gelatine capsules containing the 8-MOP in a solution. With the new galenic preparation the serum level obtained was 3.2 (P less than or equal to 0.01) times higher than with the old product. Thus, the improved resorption out of the solution was mainly responsible for these results.

[Angiotensin-converting enzyme (ACE). Increased serum activities in patients with dermatological diseases (author's transl)]. / Angiotensin-Converting Enzyme (ACE). Erhöhte Enzymaktivitäten im Serum bei dermatologischen krankheiten.

Serum activities of ACE were investigated in 40 patients with dermatological disease and in nine patients with sarcoidosis. The method of Cushman and Cheung, modified according to Lieberman, was used. Both sarcoidosis patients and patients with dermatological diseases showed marked elevations of ACE-activity. The increase in ACE-activity might result from inflammation and immunological events.

[Subcutaneous Dirofilaria (Nochtiella) repens infection in man--report of the first case in Austria and review of the literature (author's transl)]. / Subkutane Dirofilaria (Nochtiella) repens-Infektion beim Menschen--Erste Fallbeschreibung in Osterreich und Ubersicht der Literatur.

A 39-year-old female patient developed migratory skin nodules 4 months after a vacation in Greece. The patient observed a total of 17 nodules moving over the trunk to the left thigh, where a subcutaneous lesion was excised, yielding a parasite measuring 0.5 mm X 7 cm. It was classified as Dirofilaria (Nochtiella) repens. Since this is the first case observed in Austria, an exact description of subcutaneous dirofilariasis, its geographical distribution and a review of the literature is presented.

[Benzoyl peroxide in the treatment of acne vulgaris (author's transl)]. / Klinische Erfahrungen mit Benzoylperoxyd in der Behandlung der Acne vulgaris.

63 patients suffering from predominantly papulo-pustular acne vulgaris were treated with 5-10% benzoyl peroxidegel over a period of 2-4 months. The skin condition showed marked improvement in 80% of the patients. Two patients developed cutaneous allergy. Benzoyl peroxide is the therapy of choice for the inflammatory form of acne vulgaris. Systemic tetracyclines need not be given concomitantly. Autoradiographic studies revealed that benzoyl peroxide also has a truly sebostatic effect.

[Penicillamine-induced elastosis perforans serpiginosa and pulmonary cyst in Wilson's disease (author's transl)]. / Penicillamin-induzierte Elastosis perforans serpiginosa mit Lungenzyste bei Morbus Wilson.

A large air cyst was removed from the right lung of a 29-year-old female patient with Wilson's disease and penicillamine-induced perforating elastosis, the cyst first appearing after 9 years of treatment with penicillamine. Since, on the one hand, the microscopic and ultrastructural changes in the elastic tissue of the lungs were identical to those observed in the skin, both in areas of clinically-demonstrable elastosis perforans serpiginosa and clinically unaffected skin and, on the other hand, no other pulmonary disease was demonstrable to account for the development of the cystic lesion, it is concluded that penicillamine is the causative factor by means of extensive alteration of the elastic tissue. The morphological changes in the elastic fibres are so characteristic that it is easy to distinguish penicillamine-induced elastosis perforans serpiginosa from the idiopathic variant.

[Oculodermal melanocytosis (nevus of ota) and blue nevus (author's transl)]. / Okulodermale Melanozytose (Nävus Ota) und blauer Nävus.

Report is made of a patient having concurrently an Ota nevus and a blue nevus. The dermal melanocytes showed a marked formation of large intracytoplasmatic vacuoles. Reference to the important role of an "extracellular sheath" is made. The nearly identical ultrastructural characteristics of dermal melanocytes in various dermal melanocyte disorders seems to imply a common pathological origin in their development.

[Topically applied thiabendazole in the treatment of creeping eruption (cutaneous helminthiasis) (author's transl)]. / Lokalbenhandlung der "creeping eruption (Larva migrans nematosa) mit Thiabendazol.

Two patients with creeping eruption (cutaneous helminthiasis) on the feet contracted during a vacation in Ceylon were treated successfully by topical application of thiabendazole 50% in a paste destined for oral use in veterinary medicine. The preparation was applied once daily under occlusive dressings. There was no skin irritation. Prompt healing occurred after 3 and 6 days respectively. Because systemic thiabendazole therapy is frequently associated with toxic side effects, topical application seems to be the treatment of choice for creeping eruption caused by nematodes.