Detalhe da pesquisa
1.
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors.
Nucleic Acids Res
; 52(4): 2078-2090, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261989
2.
Controllable genome editing with split-engineered base editors.
Nat Chem Biol
; 17(12): 1262-1270, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663942
3.
CRISPR tiling screen reveals cancer epigenetic 'Goldilocks' state.
Trends Pharmacol Sci
; 44(9): 555-557, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328396
4.
The Base-Editing Enzyme APOBEC3A Catalyzes Cytosine Deamination in RNA with Low Proficiency and High Selectivity.
ACS Chem Biol
; 17(3): 629-636, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262324
5.
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A.
ACS Chem Biol
; 17(12): 3379-3388, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36475588