Detalhe da pesquisa
1.
GADD45A: With or without you.
Med Res Rev
; 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38264852
2.
Deletion of Gadd45a Expression in Mice Leads to Cognitive and Synaptic Impairment Associated with Alzheimer's Disease Hallmarks.
Int J Mol Sci
; 25(5)2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473843
3.
CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns.
Cell Commun Signal
; 21(1): 326, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957724
4.
A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effects.
Pharmacol Res
; 187: 106578, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36435271
5.
Design and Synthesis of AMPK Activators and GDF15 Inducers.
Molecules
; 28(14)2023 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513338
6.
SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2.
Cell Commun Signal
; 18(1): 147, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32912335
7.
PPARß/δ: A Key Therapeutic Target in Metabolic Disorders.
Int J Mol Sci
; 19(3)2018 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29558390
8.
VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells.
Diabetologia
; 60(11): 2262-2273, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835988
9.
PPARß/δ and lipid metabolism in the heart.
Biochim Biophys Acta
; 1861(10): 1569-78, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26825692
10.
Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(5): 541-551, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28214558
11.
High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents.
Biochim Biophys Acta
; 1852(9): 1687-99, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26003667
12.
PPARß/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation.
Biochim Biophys Acta
; 1852(5): 1049-58, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728706
13.
Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Biochim Biophys Acta
; 1842(9): 1556-66, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24887203
14.
Carnitine palmitoyltransferase-1 up-regulation by PPAR-ß/δ prevents lipid-induced endothelial dysfunction.
Clin Sci (Lond)
; 129(9): 823-37, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26253087
15.
PPARß/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.
Diabetologia
; 57(10): 2126-35, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25063273
16.
Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARß/δ-null mice.
Biochim Biophys Acta
; 1832(8): 1241-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23507144
17.
GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-ß1/SMAD3 pathway.
Metabolism
; 152: 155772, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38176644
18.
TNF-α inhibits PPARß/δ activity and SIRT1 expression through NF-κB in human adipocytes.
Biochim Biophys Acta
; 1821(9): 1177-85, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22683888
19.
Striking a gut-liver balance for the antidiabetic effects of metformin.
Trends Pharmacol Sci
; 44(7): 457-473, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188578
20.
Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress.
Biomed Pharmacother
; 168: 115667, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37826940