1.
Org Biomol Chem
; 10(12): 2482-5, 2012 Mar 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22344532
RESUMO
A deracemization method was developed to generate optically pure L-homoalanine from racemic homoalanine using D-amino acid oxidase and ω-transaminase. A whole cell reaction using a biphasic system converted 500 mM racemic homoalanine to 485 mM L-homoalanine (>99% ee).
Assuntos
Aminobutiratos/química , D-Aminoácido Oxidase/metabolismo , Transaminases/metabolismo , Aminobutiratos/metabolismo , Escherichia coli/química , Escherichia coli/enzimologia , Cinética , Estereoisomerismo
2.
Chem Commun (Camb)
; 47(20): 5894-6, 2011 May 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21487615
RESUMO
Racemic aromatic ß-amino acids have been kinetically resolved into (R)-ß-amino acids with high enantiomeric excess (>99%) by a novel ω-TA with ca. 50% conversion.